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Medical

Non-Invasive Haemoglobin Monitor

This is a device that enables real-time, continuous, non-invasive screening for suspected anaemia and monitoring for substantial blood loss in surgery. It removes the need for painful blood sampling and therefore the requirement for trained personnel and special facilities needed for the handling of blood samples. Additionally, a continuous haemoglobin monitor in the operating theatre will enable surgeons to more accurately estimate the levels of blood required in surgery, and consequently save significant resource.

This patented technology originates from the School of Engineering and is currently at prototype stage. The team welcomes discussions with parties interested in collaborating.

Non-Invasive Glucose Monitor

An academic team from the School of Engineering have developed the theory behind a fundamentally new approach to a real time non-invasive measurement of blood glucose based on Dynamic Pulsatile Spectroscopy (DPS), which is intended to avoid the problems of calibration and signal deconvolution associated with existing market approaches and providing an absolute measurement.

In principle, detection of a range of other blood analytes (e.g. haemoglobin, bilirubin, cholesterols) should similarly be achievable with the technology, making DPS a potential platform technology with substantially broader commercial applicability.

The team welcomes discussions with parties interested in collaborating to develop this patented technology.

Oesophageal Pulse Oximeter

An academic team from the School of Engineering has developed an oesophageal saturation (SpO2) probe. Current pulse oximeters available on the market may be unreliable in certain clinical situations when peripheral perfusion is poor, as in states of hypothermia, hypovolaemia, vasoconstriction and decreased cardiac output. Additionally, sites for pulse oximeter sensors are frequently difficult to find in neonatal patients or those with major thermal injury.

An innovative miniaturised reflectance oesophageal saturation probe, that includes two infrared emitters with peak emission wavelengths at 880nm, two red emitters with wavelengths at 655nm and a single silicon photodiode detector to detect radiation backscattered by the tissue, has been constructed and fully tested in a number of hospitals.

The team welcomes all commercial discussions and the academic team would be happy to carry out clinical testing or product validation services using evidence from real patients, in collaboration with a consortium of practitioners.

eyeVisor

eyeVisor is a hardware and software platform for a comprehensive suite of visual function testing that can be applied in a variety of public health settings ranging from screening to tertiary care. It comprises an eye projection system with wide field of view that can be worn or placed in front of the patient and interfaced to a PC thus making the system portable. The product will be a simple to use, self-calibrating platform containing a library of all the necessary eye tests, which may be used in Optometrists' clinics, potentially replacing some equipment presently required. However, it may also be taken into communities and homes and used by relatively unskilled practitioners to provide diagnosis and subsequent care for those who cannot visit Optometrists.

In eye clinics at present it is not always possible to have equipment for all eye tests. Even where regular eye tests are carried out there is high variability in the quality and repeatability of tests, a need for expensive complex equipment and a lack of trained staff, all of which may lead to a sub-optimal level of detection rates. The eyeVisor is being developed to overcome these challenges, and the team would be pleased to talk to organisations interested in collaborating to take this patented technology to market.

Healthcare Rostering Software

This is software to create electronic rosters for healthcare workers, including nurses and junior doctors. It combines sophisticated mathematical programs with a deep knowledge of personnel rostering. The method is flexible and powerful, and is designed to allow for a range of considerations including legal and contractual requirements, ergonomic guidelines and individual requests.

Software currently available on the market tends to be no more than an electronic method of creating a roster by hand, where staff chose all the duties they want to work. This is a very inefficient method and keeps staffing costs high.

City's software, developed by an academic team from Cass Business School, schedules staff in the most optimal way in order to reduce staffing costs. It equally keeps agency staff to a minimum, whilst including individual shift requests from staff.

The software is currently being trialled in care homes, but the team would be very pleased to discuss the opportunity with interested parties.

Electromagnetic Tomography

This is a project to develop image reconstruction software for the emerging class of Electromagnetic Tomography Scanners (ETS). ETS are non-invasive and do not use ionising radiation, therefore have no known harmful effects. They cost much less than other diagnostic imaging tools but suffer from the problem of fuzzy boundaries, poor image quality, inflexible output and slow computation times, when monitoring time-varying systems with deformable boundaries.

The capability of this software, originating from the School of Engineering, will radically affect the use of these scanners, and potentially other scanners, in many applications by overcoming the problems listed above. Initial applications include continuous respiratory monitoring, gastric emptying, monitoring of brain activity as well as non-medical applications.

The team would be pleased to talk to organisations interested in collaborating to commercialise this technology.

Structured Illumination Opthalmoscope

This is an innovative retinal imaging device for disease diagnosis, being developed by an academic team from the Department of Optometry.

As imaging the human retina in-vivo becomes ever more important in diagnosing ocular and systemic disease accurately at an early stage of progression, most research is focussed on improving the existing high-resolution ophthalmic imaging techniques, at the expense of developing new technologies. The Structured Illumination Ophthalmoscope (SIO) can provide high resolution imaging of the human retina with strong optical sectioning capabilities for retinal tomography. It overcomes some key limitations of existing technologies such as signal to noise ratios, distortion due to intra-acquisition eye movements and complexity. These improvements will enable a simple, inexpensive instrument to be developed with better image quality than existing techniques making wider and more accurate ophthalmic screening possible.

The team would be pleased to talk to organisations interested in collaborating to commercialise this patented technology.

PaperChain

PaperChain is an electronic system designed to support the real-time sharing of clinical information for paediatric ambulance transport services in London. An academic team from the Centre for HCI Design has developed this life-saving system to improve the information shared between "handoff" teams of physicians and paramedics.

Paediatric ambulance services transport critically ill children from regional hospitals that do not have intensive care facilities to the paediatric intensive care units of major London hospitals. These services also provide advice on the treatment of children either prior to transporting them or instead of doing so, in situations where transport is deemed inappropriate. The services are staffed by doctors and nurses, and the transport or "retrieval" of each child is a collaborative activity involving multiple healthcare professionals.

The system makes use of an electronic pen to record information on paper and transmits it electronically to a server where it can be accessed and viewed remotely by a clinician using a PC and browser. This system has the potential to be applied in a wide range of clinical and industrial applications.

The technology has been successfully trialled and the team would be pleased to talk to any parties interested in discussing a license.

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City, University of London is an independent member institution of the University of London. Established by Royal Charter in 1836, the University of London consists of 18 independent member institutions with outstanding global reputations and several prestigious central academic bodies and activities.