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School of Mathematics, Computer Science & Engineering

Research Centre for Biomedical Engineering

Creating biomedical technologies, from design to the patient.

The Research Centre for Biomedical Engineering (RCBE) offers world-class research in state-of-the-art laboratories where engineers, scientists and healthcare experts work together to develop new medical technologies to solve some of the most urgent and challenging problems in healthcare.

About the centre

The Research Centre for Biomedical Engineering (RCBE) at City, University of London was founded in the mid-90s with the aim of pursuing research in the emerging field of Biomedical Engineering, a discipline that applies the principles of physics and engineering to the complex medical devices used in the diagnosis and treatment of the sick and injured. The Centre occupies state of the art laboratories and has built a global reputation, offering world-class facilities and expertise to researchers and collaborators including scientists, engineers and clinicians from around the world. Working in close partnership with leading hospitals and healthcare technology companies, researchers in the Centre develop medical devices, biosensors, and signal and image processing techniques for applications across a wide range of medical specialities, addressing patients’ and societal needs including breakthroughs in diagnosis, monitoring, treatment and prevention of disease.

Our shared vision is to develop novel medical technologies to address some of the main challenges in global healthcare including;

  • the early non-invasive screening of cardiovascular diseases
  • non-invasive blood and tissue biochemistry
  • diagnostic and monitoring technologies in mental health
  • technologies for improved clinical monitoring and management of neurodegenerative conditions

Main Areas of Research

Click on the name of the area of research to learn more.

Biomedical optical sensing

The Biomedical Optical Sensing Group has over two decades of knowledge in the areas of tissue optics, haemodynamics, vascular mechanics, multi-wavelength photoplethysmography, static and dynamic spectrophotometry, in vitro modelling and chemometrics. This knowledge is applied to the design and development of novel optical sensors and medical instrumentation for use in a wide range of applications including pulse oximetry, tissue and organ perfusion, cerebral/muscle near infrared spectroscopy, tissue gas measurement and non-invasive monitoring of blood analytes and disease biomarkers.

The underpinning focus of the group’s activity is to elicit broad understanding of the physics of the light-tissue interaction applicable to optical path determination, spatial intensity distribution and propagation dynamics through biological tissue structures.   These models are validated by rigorous in vitro and in vivo experimental work using cardiovascular circuits and tissue phantoms to evaluate sensor designs. Specific areas of experimentation include evaluation and parametric characterisation of light sources, detectors, free optics and fibreoptic sensor systems, conventional spectroscopy studies on biomaterials, volumetric and directional photometry and spectrometry in scattering media.

The design of novel sensors for use in a wide range of applications is based on the data generated by these models.  Experimentation with novel optoelectronic materials enables technological advancements such as miniaturisation, reduced power consumption and improved biocompatibility of implantable sensors.  The advancements open new avenues of research and clinical application of non-invasive diagnostic technologies.

Optical and Impedance spectroscopy

The Optical Spectroscopy Group is devoted to understanding the optical properties of biological media and tissue, with the aim of developing the next generation of multi-wavelength optical sensors for biomedical applications. The laboratory houses various spectroscopic instruments and techniques to conduct such work. This includes sophisticated UV-Vis-NIR and FTIR, fluorescence and flame photometry instrumentation, whilst expert techniques include fibre optic handling and dip-coating, and micro-volume sampling.  The work carried out involves in vivo, in vitro and ex vivo testing of concentration, and identifies the spectroscopic ‘signatures’ of various gases and analytes of interest. This serves as the basis of biosensor design and development for physiological monitoring or disease diagnosis. Instrument and sensor evaluations are often carried out on human volunteers and through clinical trials.

The Impedance Spectroscopy Group carries out blood analysis research, mainly towards increasing sensitivity to small variations of analytes, such as lithium, which is used extensively by bipolar patients. Impedance instrumentation research includes the use of FEM simulations (COMSOL) for the design and assessment of electrode topologies and fluidic channel designs, as well as design of circuits for improved sensitivity, impedance range and frequency range in application-specific solutions. Some of the instrumentation includes analogue electronic circuit design for waveform generation and differential output ac current sources, as well as mixed-signal design for multi-electrode adjustable topologies. Combining both optical and impedance spectroscopy allows spectra to be ‘cross referenced’ to detect specific low-concentration analytes with unprecedented sensitivity.

Neural interfacing and Neuroprosthetics

The Neural interfacing and Neuroprosthetics Group exploits the electrical and other physical (e.g. thermal) properties of excitable and non-excitable tissues for the aim of developing integrated devices for targeted rehabilitation, with minimal side-effects.The aim is to develop a peripheral nerve stimulation method that will activate either exclusively sensory or exclusively motor neural pathways, using combined electrical and optical stimuli.

The motivation is to replace present stimulation techniques - which activate simultaneously sensory and motor nerve signals - with the proposed method, in order to eliminate related side-effects thus eventually allowing for its wider use in mainstream clinical practice for disease-specific and event-triggered therapeutic intervention in both chronic and intraoperative conditions.

The group also employs multi-electrode topologies and dedicated adjustable-waveform current injection electronics. Therapeutic effects of electrical stimulation in wound healing are also being researched using the knowledge and instrumentation developed for neural interfaces. This is done in conjunction with device miniaturisation through integrated circuit (IC) design in 0.35µm CMOS technology.

Biomedical signal and image processing

The Biomedical Signal and Image Processing Group works on establishing novel and sophisticated computational and mathematical tools to deal with challenging biomedical data sets, such multi-dimensional data sets, as well as to integrate information from multiple biomedical modalities at different scales, i.e. from macroscopic levels to microscopic levels like histopathology and biometrics.

The group also utilises advance linear and non-linear signal processing techniques such as Time-Frequency Distribution (TFD), Empirical Mode Decomposition (EMD) etc., to extract features from biosignals, such as Electrocardiograph (ECG), Photoplethysmograph (PPG), and Near-infrared Spectroscopy (NIRS), that will provide useful physiological information related to the haemodynamic and cardiovascular state of a person.

The image processing activities of the group utilise open-source software (www.phagosight.org) and on-line repositories of cancer image analysis (www.caiman.org.uk) to produce specialised algorithms, in particular: Segmentation and Tracking of Immune Cells, Measurement of Microvascular Permeability, Tissue Texture Segmentation and Classification, Feature Selection for Multidimensional Data Sets, automated segmentation of vasculature and stenosis grading, multi-scale reconstruction of Electrical Impedance Tomography images. The group also promotes soft field imaging modalities as an alternative to the use of ionising radiation through the development of a unified theoretical framework for the Forward and Inverse problems.

Biomedical Instrumentation

Design of biomedical instrumentation is at the heart of our research activities. Medical devices must meet exceptionally high standards of reliability and precision under demanding conditions.  They must also be ergonomic, intuitive and adhere to rigorous standards of patient safety, accuracy and quality control. Devices, such as patient monitoring systems, are sometimes custom-made for specific projects, or flexible multi-channel monitoring platforms may be adapted to a specific application.  Our medical instruments are designed using a ‘top-down’ approach, where the medical application and needs of the patient are considered from the earliest stages of the design process.  Discrete and integrated circuits, power supplies, interfaces and housings may be designed and fabricated in house.  Novel sensor technologies are designed in the Centre and where necessary are mass-produced by our industrial collaborators.

Research projects

Click on a project title to read more

Project Principal investigator(s)
[Co-investigator(s)]
Researcher(s)
Personal Lithium Blood Level Analyser for patients with Bipolar Mood Disorder Prof P A Kyriacou Dr M Qassem, Dr L Constantinou
Development of a multi-parameter oesophageal sensor for the early detection of Multiple Organ Dysfunction Syndrome (MODS) Prof P A Kyriacou Dr J Davenport
Non-invasive optical sensors for the monitoring of cerebral oxygenation and detection of Hypoxic Ischaemic Encephalopathy (HIE) in neonates Prof P A Kyriacou Dr J May
A non-invasive optical intracranial pressure monitoring system Dr J P Phillips  
Non-invasive Optical sensor for the monitoring of Blood Glucose in diabetes Prof P A Kyriacou Dr V Rybynok
Image analysis for neutrophils and other cells Dr C Reyes-Aldasoro Mr J Solis-Lemus
Improved Healing by combining Optical and Electrical Stimulation of Nerves (HOpES) Dr I. Triantis Dr E. Rahman
Spectrophotometric Techniques for the Assessment of Tissue Perfusion in Plastic Surgery Prof P A Kyriacou Mr T Abay Ysehak, Dr Tina Zaman, Dr M Hickey
An Intelligent Intervertebral Disc Prosthesis for the Assessment of Spinal Loading Prof P A Kyriacou Dr M Pancholi
NHS:My Care (Electronic Personalised Medical Records) Prof P A Kyriacou, Prof A Woodcock (Coventry University) Dr V Rybynok, Dr J Binnersley (Coventry University)
Fibre-optic Sensor for Measuring Splanchnic Blood Perfusion Prof P A Kyriacou  
Relationship between plasma concentrations of Lignocaine, Bupivacaine and heart rate variability in patients undergoing transarterial axillary plexus blockade Prof P A Kyriacou Dr K Shafqat
Novel oesophageal blood oxygen sensors in adult and neonatal monitoring Prof P Kyriacou  
Modelling of light tissue interactions in Photoplethysmography Dr J Phillips, Prof P Kyriacou Ms S Chatterjee
In vivo and in vitro investigations of skin hydration and barrier function using Near Infrared Spectroscopy (NIRS) Prof P A Kyriacou Dr M Qassem
Optical imaging and optical spectroscopy investigating Necrotizing enterocolitis (NEC) in neonates Professor P Kyriacou  
Development and assessment of a novel intra-luminal sensor for monitoring intestinal viability in colorectal cancer surgery Prof P A Kyriacou Miss Z Patel
Optical sensors for continuous monitoring of cerebrospinal fluid pulsations in neonatal hydrocephalus Prof P Kyriacou, Dr M Hickey  
Blood flow phenomenon in arteries using coupled field analysis. Prof P A Kyriacou, Prof. R Pai B, Manipal University, India Mr N Kumar
Photoplethysmography in the assessment of blood flow and vascular mechanics Prof P A Kyriacou Ms H Njoum
Development of a digital wearable multiwavelength photoplethysmograhic (PPG) system for the Investigation of muscle perfusion Prof P A Kyriacou Mr M Razban
Application of phononic crystals as liquid sensors Prof P Kyriacou (City University London); Prof R T Villa (Escuela de Ingeniería de Antioquia, Colombia) Mr S Villa
Non Invasive monitoring of Blood pressure utilizing the photoplethysmograph Prof P Kyriacou (City University London); Prof R T Villa (Escuela de Ingeniería de Antioquia, Colombia) Mr B Escobar
Reflectance Photoplethysmography as Noninvasive Monitoring of Tissue Blood Perfusion Prof P Kyriacou T Y Abay
Evaluation of a combined laser Doppler and photoplethysmographic system for intra-operative monitoring of bowel tissue viability Dr J P Phillips Dr Z Abdollahi
Development and evaluation of the 'Sensing ET Tube' for multi-parameter monitoring. Dr J May  
Investigating the relations of the Photoplethysmogram with cardiovascular changes Dr M Hickey, Dr J Phillips, Prof P Kyriacou  
Assessment of splanchnic perfusion using an intra-luminal opto-electronic probe placed at the duodenum Prof P Kyriacou Dr C Gama, Dr A Belhaj
In vivo investigations of photoplethysmograms and arterial oxygen saturation from the auditory canal in conditions of compromised peripheral perfusion Prof P Kyriacou Mr K Budidha
An optical fibre system for monitoring blood oxygen saturation of brain tissue Dr J Phillips  
Advanced Photoplethysmographic Instrumentation: ZenPPG Dr V Rybynok, Prof P Kyriacou, Dr J Phillips, Dr M Hickey Mr K Budidha, Dr J May,
Optical assessment of spinal cord haemodynamics in animal models of spinal cord injury Dr J Phillips  
Photoplethysmographic signals and blood oxygen saturation during artificially induced peripheral hypoperfusion utilising multimodal photoplethysmography sensors Prof P Kyriacou Dr M Shafique

Portrait of Justin Phillips

Dr Justin Phillips

Potential research student projects

Potential Research Student Projects

PhD candidates carry out Biomedical Engineering research in the Department of Electrical & Electronic Engineering. Potential research student projects in the field of Biomedical Engineering are shown below, for more details, click on the name of the project. Find out more about applying to a research degree in this field.

Click on the project title for more information

Wearable sensors: Technologies for globalised healthy living and wellbeing

Professor P. A. Kyriacou

The vision of the proposed research programme lies in the design, development and implementation of non-invasive sensing technologies with wide applications, as will be described below, in both the clinical and the home setting. Such sensing technologies could be used for monitoring, prognostic (screening), diagnostic and therapeutic purposes.  The global sensors market is estimated at over $44billion and with sensors being integrated into an increasingly diverse array of applications, smaller, smarter, lighter and cheaper sensors have more growth potential. Modern applications of sensing systems require the establishment of reliable, low-power wireless networks of sensors which are data-centric, with sensor nodes communicating only when necessary to transport data.  The development of such technologies are in line with the strategic plan of NHS and other similar organisations, which is to drive the more mundane delivery of health care, outside the hospitals and in the community. Technologies for screening, monitoring, etc. will alleviate the congestion of health care centres and it will enable them to concentrate in critical care interventions. Recording of physiological and psychological variables in real-life conditions could be especially useful in management of chronic disorders or other health problems e.g. for high blood pressure, diabetes, anorexia nervosa, chronic pain or severe obesity, stress, epilepsy, depression and many others.

Point-of-care non-invasive blood and tissue biochemistry

Professor P. A. Kyriacou, Dr J. Phillips, Dr I. Triantis, Dr M. Hickey

The focus of this project is to develop non-invasive optical rapid measurements and/or continuous monitoring of biological variables currently only measurable via blood samples or invasive techniques (i.e. concentrations of chromophores, gases, hormones, ionic salts, enzymes, lipids, and other biomarkers relating to organ function, stress, mood disorders, etc., within biological tissues and blood). This will be made possible by applying optical and electrical impedance spectroscopic techniques.

Non-invasive screening of cardiovascular diseases

Professor P. A. Kyriacou, Dr J. Phillips, Dr I. Triantis, Dr M. Hickey

The main objectives of this project are to develop multi-parameter sensors, and signal processing techniques for the non-invasive and continuous mapping of physiological and haemodynamic parameters. The output will be the non-invasive screening of pathologies relating to cardiovascular diseases (peripheral vascular (artery/vein) disease, lower limb claudication, atherosclerosis, carotid artery disease, hypertension, stroke, etc.). Some of the targeted parameters will be pulse transit time (PTT), pulse wave velocity (PWV), blood flow, blood volume, arterial and venous oxygen saturation, blood pressure, etc.

Point-of-care diagnostic and monitoring technologies in mental health

Professor P. A. Kyriacou, Dr J. Phillips, Dr I. Triantis, Dr M. Hickey

This work proposes the development of new sensitive and accurate point-of-care (POC) diagnostic and monitoring portable devices for use by mood disorder patients at home. These technologies will allow for the quantification of (a) pharmaceutical blood levels ensuring that patients maintain a therapeutic state and are not at danger of toxicity-related complications, and (b) stress biomarkers which correlate with possible depressive relapses in mood disorder patients, allowing for timely intervention. An inter-disciplinary team with expertise in MEMS, biomedical sensors, biochemistry and psychopharmacology has been established to provide these solutions. The POC devices will include miniaturised sensor platforms for depositing drops of blood/saliva, optical and electrical impedance sensors to interrogate the sample, portable instrumentation, and algorithms to rapidly determine concentration levels. Such devices will have a significant impact on clinical decisions and health outcomes for mood disorder patients.

Sensing for diagnosis of dementia

Professor P. A. Kyriacou, Dr J. Phillips, Dr M. Hickey

This project supports fundamental research in sensing targeted specifically at the diagnosis of dementias and the quantitative measurement of disease progression. The aim is to deliver non-invasive and cost effective solutions with applications making a clear contribution to one or more of the following:

  • Technologies/techniques which more accurately and easily differentiate dementia sub-types. Applications which focus on prodromal, presymptomatic stages of the disease are particularly welcomed.
  • Technologies/techniques which enable quantitative measurement of disease progression of dementia.

Central nervous system addressing through peripheral neural pathways

Dr I. Triantis

Develop peripheral nervous system implants that will utilise sensory neural pathways as probes into the brain and the spinal cord, while minimising the effects on the periphery. Examples include Vagus nerve stimulators that can be used for a range of diseases including epilepsy, Alzheimer’s, depression and Parkinson’s disease. The methods developed will have a range of benefits, from the neuroscience perspective, gaining invaluable insights into the neural pathways that provide access to deep brain structures; to clinical practices, where signals from the brain are used as triggers for preventive stimulation providing fully automated symptom suppression.

Technological solutions in wound healing

Dr I. Triantis, Professor P. A. Kyriacou

Rapid healing of wounds, including those that relate to surgery or injury, as well as those that occur due to a disease, e.g. diabetic ulcers. The benefits will be enormous both for patients and for the health system, by respectively reducing mortality and infection and reducing the time of hospitalisation and the enormous use of resources necessary for conventional treatment. Application specific optical spectroscopy and electrical stimulation will be utilised in combination with “smart” dressings that will feature embedded miniaturised multi-modal sensors for real time monitoring of the condition of the wound.

Advanced biosignal analysis from multiparameter physiological dataset

Professor P. A. Kyriacou

The recent advancements in physiological sensors (optical and electrical) have enabled the acquisition of physiological data non-invasively which was not possible in the past. With the help of such a multiparameter dataset it might be possible, utilising advance linear and non-linear signal processing techniques such as Time-Frequency Distribution (TFD), Empirical Mode Decomposition (EMD) etc., to extract features that will provide useful physiological information related to the haemodynamic and cardiovascular state of a person. The combined information obtained from different non-invasive modalities such as Electrocardiograph (ECG), Respiration, Photoplethysmograph (PPG), Blood pressure (BP) and Near-infrared Spectroscopy (NIRS) can be beneficial and has a significant impact in various fields such as anaesthesia management, paediatric care and sports medicine. This work is in collaboration with national and international partners including St Bartholomew’s Hospital, The Royal London Hospital, Great Ormond street hospital for Children and Yale School of medicine.

Immunohistochemistry of Brain Tumours

Dr Constantino Carlos Reyes-Aldasoro

Abnormal growth of cells inside the brain is relatively rare, but serious and life threatening when it leads to brain tumours. Recent research has shown that certain features of certain tumours are probably important in predicting their response to treatment, but the relationship between the different features is so complicated that this information cannot yet be used to help patients. This multidisciplinary proposal will investigate in detail how various characteristics of brain tumours impact on patient outcome. The aims of this project are to obtain quantitative measurements from the images of tumour specimens and evaluate which measurements, or sets of measurements, correlate best with patient outcomes such as life expectancy and response to treatment.

This project requires programming image analysis algorithms in Matlab to segment the different cells in tumours stained by immunohistochemical techniques. The ideal student should have good programming skills in Matlab, should have a good knowledge of image analysis and interest in biomedical imaging.  Previous biological knowledge is not required but an interest to learn is essential.

Analysis of Bees' behaviour

Dr Constantino Carlos Reyes-Aldasoro

This project is a collaboration with the laboratory of social insects of the University of Sussex (http://www.sussex.ac.uk/lasi). The aims of this project are to extract information regarding the complex behaviour of bees from their movements from videos, in order to do that it is necessary to develop segmentation and tracking algorithms. This is a very challenging problem as the images of the bees are complex and difficult to analysed through algorithms. This project requires programming image analysis algorithms in Matlab to segment and track the movements of the Bees. The ideal student should have good programming skills in Matlab, should have a good knowledge of image analysis and interest in biomedical imaging.

For more information, including how to apply, please see the research degree course page for the Department of Electrical & Electronic Engineering.

Portrait of Iasonas Triantis

Dr Iasonas Triantis

Publications

Publications

Members of RCBE have authored and co-authored over 500 publications in high impact engineering, science and clinical journals, prestigious international conferences, invited chapters in books, books and monographs. On average, 10 papers per year are presented at the main IEEE conferences and some clinical conferences. A selective group of conferences that the centre makes a significant contribution are: IEEE EMBC, IEEE Sensors, IEEE International Symposium in Biomedical Imaging, IEEE International Conference in Image Processing, IEEE Biomedical Circuits and Systems, Annual International Conference on Cardiology & Cardiovascular Medicine Research, and World Congress of Cardiology. Members of the Centre also currently hold several patents with inventions in the area of Biomedical Instrumentation and Optical Biomedical Sensors.

Up-to-date list of publications

Rahman, E., Powner, M. B. ORCID: 0000-0003-4913-1004, Kyriacou, P. A. ORCID: 0000-0002-2868-485X and Triantis, I. ORCID: 0000-0002-8900-781X (2018). Assessment of the Complex Refractive Indices of Xenopus Laevis Sciatic Nerve for the Optimisation of Optical (NIR) Neurostimulation. IEEE Transactions on Neural Systems and Rehabilitation Engineering, doi: 10.1109/TNSRE.2018.2878107

Olliverre, N. J., Yang, G., Slabaugh, G.G., Reyes-Aldasoro, C. C. ORCID: 0000-0002-9466-2018 and Alonso, E. (2018). Generating Magnetic Resonance Spectroscopy Imaging Data of Brain Tumours from Linear, Non-Linear and Deep Learning Models. In: Simulation and Synthesis in Medical Imaging. Lecture Notes in Computer Science (11037). (pp. 130-138). Cham, Switzerland: Spirnger. ISBN 978-3-030-00535-1

Karabag, C., Jones, M. L., Peddie, C. J., Weston, A. E., Collinson, L. M. and Reyes-Aldasoro, C. C. ORCID: 0000-0002-9466-2018 (2018). Automated Segmentation of HeLa Nuclear Envelope from Electron Microscopy Images. Communications in Computer and Information Science, doi: 10.1007/978-3-319-95921-4_23

Miller, N. R., Verhoeven, J. ORCID: 0000-0002-0738-8517 and Reyes-Aldasoro, C. C. ORCID: 0000-0002-9466-2018 (2018). Analysis of the symmetry of electrodes for Electropalatography with Cone Beam CT Scanning. Communications in Computer and Information Science, 2018, pp. 130-139. doi: 10.1007/978-3-319-95921-4_14

Solis-Lemus, J. A., Stramer, B., Slabaugh, G.G. and Reyes-Aldasoro, C. C. ORCID: 0000-0002-9466-2018 (2018). Analysis of the Interactions of Migrating Macrophages. Communications in Computer and Information Science, 2018, pp. 262-273. doi: 10.1007/978-3-319-95921-4_25

Chatterjee, S., Abay, T. Y., Phillips, J. P. ORCID: 0000-0003-3486-3704 and Kyriacou, P. A. ORCID: 0000-0002-2868-485X (2018). Investigating optical path and differential pathlength factor in reflectance photoplethysmography for the assessment of perfusion. Journal of Biomedical Optics, 23(7), .075005. doi: 10.1117/1.JBO.23.7.075005

Qassem, M., Constantinou, L., Triantis, I. ORCID: 0000-0002-8900-781X, Hickey, M., Palazidou, E. and Kyriacou, P. A. ORCID: 0000-0002-2868-485X (2018). A Novel Method for Low-Volume Measurement of Lithium in Human Blood to use in Personalized Monitoring of Lithium Treatment.. IEEE Transactions on Biomedical Engineering, doi: 10.1109/TBME.2018.2836148

Kather, J. N., Berghoff, A. S., Ferber, D., Suarez-Carmona, M., Reyes-Aldasoro, C. C. ORCID: 0000-0002-9466-2018, Valous, N. A., Rojas-Moraleda, R., Jäger, D. and Halama, N. (2018). Large-scale database mining reveals hidden trends and future directions for cancer immunotherapy. OncoImmunology, doi: 10.1080/2162402X.2018.1444412

Budidha, K. ORCID: 0000-0002-6329-8399, Rybynok, V and Kyriacou, P. A. ORCID: 0000-0002-2868-485X (2018). Design and Development of a Modular, Multichannel Photoplethysmography System. IEEE Transactions on Instrumentation and Measurement, 67(8), pp. 1954-1965. doi: 10.1109/TIM.2018.2810643

Leandrou, S., Petroudi, S., Reyes-Aldasoro, C. C., Kyriacou, P. A. and Pattichis, C. S. (2018). Quantitative MRI Brain Studies in Mild Cognitive Impairment and Alzheimer's disease: A Methodological Review. IEEE Reviews in Biomedical Engineering, PP(99), doi: 10.1109/RBME.2018.2796598

Jawaid, M. M., Narejo, S., Pirzada, N., Baloch, J., Reyes-Aldasoro, C. C. ORCID: 0000-0002-9466-2018 and Slabaugh, G.G. (2018). Automated quantification of non-calcified coronary plaques in cardiac CT angiographic imagery. International Journal of Advanced Computer Science and Applications, 9(7), pp. 216-222. doi: 10.14569/IJACSA.2018.090731

Njoum, H. and Kyriacou, P. A. (2018). In vitro validation of measurement of volume elastic modulus using photoplethysmography. Medical Engineering & Physics, 52, pp. 10-21. doi: 10.1016/j.medengphy.2017.11.011

Patel, Z., Thaha, M. A. and Kyriacou, P. A. ORCID: 0000-0002-2868-485X (2018). The effects of optical sensor-tissue separation in endocavitary photoplethysmography. Physiological Measurement, 39(7), 075001.. doi: 10.1088/1361-6579/aacc1d

Qassem, M., Triantis, I. ORCID: 0000-0002-8900-781X, Hickey, M., Palazidou, E. and Kyriacou, P. A. ORCID: 0000-0002-2868-485X (2018). Methodology for rapid assessment of blood lithium levels in ultramicro volumes of blood plasma for applications in personal monitoring of patients with bipolar mood disorder. Journal of Biomedical Optics (JBO), 23(10), 107004.. doi: 10.1117/1.JBO.23.10.107004

Reyes-Aldasoro, C. C. ORCID: 0000-0002-9466-2018 (2018). Shape Analysis and Tracking of Migrating Macrophages. Poster presented at the IEEE International Symposium on Biomedical Imaging (ISBI), 4-7 Apr 2018, Washington, D.C., USA.

Solis-Lemus, J. A., Stramer, B., Slabaugh, G.G. and Reyes-Aldasoro, C. C. ORCID: 0000-0002-9466-2018 (2018). Shape analysis and tracking of migrating macrophages. 2018 IEEE 15th International Symposium on Biomedical Imaging (ISBI 2018), pp. 1006-1009. doi: 10.1109/ISBI.2018.8363741

Villa-Arango, S., Betancur, D., Torres, R. and Kyriacou, P. A. ORCID: 0000-0002-2868-485X (2018). Use of Transient Time Response as a Measure to Characterize Phononic Crystal Sensors. Sensors, 18(11), 3618.. doi: 10.3390/s18113618

Constantinou, L., Kyriacou, P. A. ORCID: 0000-0002-2868-485X and Triantis, I. ORCID: 0000-0002-8900-781X (2017). Towards an Optimized Tetrapolar Electrical Impedance Lithium Detection Probe For Bipolar Disorder: A Simulation Study. In: Sensors, 2017 IEEE. . IEEE. ISBN 9781509010127

Constantinou, L., Kyriacou, P. A. ORCID: 0000-0002-2868-485X and Triantis, I. (2017). Towards an optimized tetrapolar electrical impedance lithium detection probe for bipolar disorder: A simulation study. 2017 IEEE SENSORS, 2017-D, doi: 10.1109/ICSENS.2017.8234225

Solis-Lemus, J. A., Stramer, B., Slabaugh, G.G. and Reyes-Aldasoro, C. C. ORCID: 0000-0002-9466-2018 (2017). Segmentation and Shape Analysis of Macrophages Using Anglegram Analysis. Journal of Imaging, 4(1), doi: 10.3390/jimaging4010002

Patel, Z., Thaha, M. A. and Kyriacou, P. A. (2017). Development of an intraluminal intestinal photoplethysmography sensor. Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, pp. 1840-1843. doi: 10.1109/EMBC.2017.8037204

Reyes-Aldasoro, C. C. and Slabaugh, G.G. (2017). Special issue: medical image understanding and analysis. Computer Methods in Biomechanics and Biomedical Engineering: Imaging and Visualization, 5(5), p. 317. doi: 10.1080/21681163.2015.1081080

Saadat Beheshti, S. M. R., Liatsis, P. and Rajarajan, M. (2017). A CAPTCHA model based on visual psychophysics: Using the brain to distinguish between human users and automated computer bots. Computers and Security, 70, pp. 596-617. doi: 10.1016/j.cose.2017.08.006

Reyes-Aldasoro, C. C. (2017). The proportion of cancer related entries in PubMed has increased considerably. Paper presented at the 2017 NCRI Conference, 5-8 Nov 2017, Liverpool, UK.

Chatterjee, S., Phillips, J. P. and Kyriacou, P. A. (2017). Investigating optical path in reflectance pulse oximetry using a multilayer monte carlo model. SPIE Proceedings, 10411, doi: 10.1117/12.2281612

Jawaid, M.M., Rajani, R., Liatsis, P., Reyes Aldasoro, C. and Slabaugh, G.G. (2017). Improved CTA Coronary Segmentation with a Volume-Specific Intensity Threshold. Paper presented at the Medical Image Understanding and Analysis (MIUA) 2017, 11 Jul 2017, Edinburgh, UK.

Abay, T. Y. and Kyriacou, P. A. (2017). Photoplethysmography for blood volumes and oxygenation changes during intermittent vascular occlusions. Journal of Clinical Monitoring and Computing, doi: 10.1007/s10877-017-0030-2

Solis Lemus, J., Stramer, B., Slabaugh, G.G. and Reyes-Aldasoro, C. C. (2017). Segmentation of Overlapping Macrophages Using Anglegram Analysis. Paper presented at the Medical Image Understanding and Analysis (MIUA) 2017, 11 Jul 2017, Edinburgh, UK.

Jawaid, M.M., Rajani, R., Liatsis, P., Reyes-Aldasoro, C. C. and Slabaugh, G.G. (2017). A Hybrid Energy Model for Region Based Curve Evolution - Application to CTA Coronary Segmentation. Computer Methods and Programs in Biomedicine, doi: 10.1016/j.cmpb.2017.03.020

Reyes-Aldasoro, C. C. (2017). The proportion of cancer-related entries in PubMed has increased considerably; is cancer truly "The Emperor of All Maladies"?. PLoS One, 12(3), e0173671.. doi: 10.1371/journal.pone.0173671

Constantinou, L., Triantis, I., Hickey, M. and Kyriacou, P. A. (2017). On the merits of tetrapolar impedance spectroscopy for monitoring lithium concentration variations in human blood plasma. IEEE Transactions on Biomedical Engineering, 64(3), pp. 601-609. doi: 10.1109/TBME.2016.2570125

Villa-Arango, S., Torres Villa, R., Kyriacou, P. A. and Lucklum, R. (2017). Fully-disposable multilayered phononic crystal liquid sensor with symmetry reduction and a resonant cavity. Measurement: Journal of the International Measurement Confederation, 102, pp. 20-25. doi: 10.1016/j.measurement.2017.01.051

Budidha, K. and Kyriacou, P. A. (2017). In vivo investigation of ear canal pulse oximetry during hypothermia. Journal of Clinical Monitoring and Computing, doi: 10.1007/s10877-017-9975-4

Hashim, Z.Q., Constantinou, L., Kyriacou, P. A. and Triantis, I. (2017). A novel approach to transcutaneous localization of blood vessels using a dynamically reconfigurable electrode (DRE) array. In: 2016 IEEE Biomedical Circuits and Systems Conference (BioCAS). . Institute of Electrical and Electronics Engineers (IEEE). ISBN 9781509029594

Villa-Arango, S., Torres, R., Kyriacou, P. A. and Lucklum, R. (2017). Acoustic spectrometer: Resonant sensing platform for measuring volumetric properties of liquid samples. IFMBE Proceedings, 60, pp. 70-73. doi: 10.1007/978-981-10-4086-3_18

Davenport, J. J., Hickey, M., Phillips, J. P. and Kyriacou, P. A. (2017). Dual pO₂/pCO₂ fibre optic sensing film. The Analyst, 142(10), pp. 1711-1719. doi: 10.1039/C7AN00173H

Jawaid, M.M., Riaz, A., Rajani, R., Reyes-Aldasoro, C. C. and Slabaugh, G.G. (2017). Framework for Detection and Localization of Coronary Non-Calcified Plaques in Cardiac CTA using Mean Radial Profiles. Computers in Biology and Medicine, 89, pp. 84-95. doi: 10.1016/j.compbiomed.2017.07.021

Njoum, H. (2017). Investigations of photoplethysmography in the assessment of haemodynamics, vascular mechanics and haemorheology. (Unpublished Doctoral thesis, City, University of London)

Njoum, H. and Kyriacou, P. A. (2017). Photoplethysmography for the Assessment of Haemorheology. Scientific Reports, 7, 1406.. doi: 10.1038/s41598-017-01636-0

Papadopoulos, N., Kyriacou, P. A. and Damianou, C. (2017). Review of Protocols Used in Ultrasound Thrombolysis. Journal of Stroke and Cerebrovascular Diseases, 26(11), pp. 2447-2469. doi: 10.1016/j.jstrokecerebrovasdis.2017.07.032

Reyes-Aldasoro, C. C., Björndahl, M. A., Kanthou, C. and Tozer, G. M. (2017). Topological analysis of the vasculature of angiopoietin-expressing tumours through scale-space tracing. Communications in Computer and Information Science, 723, pp. 285-296. doi: 10.1007/978-3-319-60964-5_25

Ulman, V., Maska, M., Magnusson, K. E. G., Ronneberger, O., Haubold, C., Harder, N., Matula, P., Matula, P., Svoboda, D., Radojevic, M., Smal, I., Rohr, K., Jalden, J., Blau, H. M., Dzyubachyk, O., Lelieveldt, B., Xiao, P., Li, Y., Cho, S-Y., Dufour, A C., Olivo-Marin, J-C., Reyes-Aldasoro, C. C., Solis-Lemus, J. A., Bensch, R., Brox, T., Stegmaier, J., Mikut, R., Wolf, S., Hamprecht, F. A., Esteves, T., Quelhas, P., Demirel, O., Malmstrom, L., Jug, F., Tomancak, P., Meijering, E., Munoz-Barrutia, A., Kozubek, M. and Ortiz-de-Solorzano, C. (2017). An objective comparison of cell-tracking algorithms. Nature Methods, 14(12), pp. 1141-1152. doi: 10.1038/nmeth.4473

Villa-Arango, S., Betancur Sánchez, D., Torres, R., Kyriacou, P. A. and Lucklum, R. (2017). Differential Phononic Crystal Sensor: Towards a Temperature Compensation Mechanism for Field Applications Development. Sensors, 17(9), 1960.. doi: 10.3390/s17091960

Chatterjee, S., Phillips, J. P. ORCID: 0000-0003-3486-3704 and Kyriacou, P. A. ORCID: 0000-0002-2868-485X (2016). Monte Carlo investigation of the effect of blood volume and oxygen saturation on optical path in reflectance pulse oximetry. Biomedical Physics and Engineering Express, 2(6), 065018. doi: 10.1088/2057-1976/2/6/065018

Belhaj, A., Phillips, J. P., Kyriacou, P. A. and Langford, R. M. (2016). Comparison of non-invasive peripheral venous saturations with venous blood co-oximetry. Journal of Clinical Monitoring and Computing, doi: 10.1007/s10877-016-9959-9

Njoum, H. and Kyriacou, P. A. (2016). Photoplethysmography: Towards a non-invasive pressure measurement technique. IEEE, doi: 10.1109/EMBC.2016.7590776 ISSN 1558-4615

Qassem, M., Hickey, M. and Kyriacou, P. A. (2016). Colorimetric determinations of lithium levels in drop-volumes of human plasma for monitoring patients with bipolar mood disorder. Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, 2016, doi: 10.1109/EMBC.2016.7591889

Fonseca, J., Nadimi, S., Reyes-Aldasoro, C. C., O’Sullivan, C. and Coop, M. R. (2016). Image-based investigation into the primary fabric of stress transmitting particles in sand. Soils and Foundations, 56(5), pp. 818-834. doi: 10.1016/j.sandf.2016.08.007

Hickey, M., Phillips, J. P. and Kyriacou, P. A. (2016). Investigation of peripheral photoplethysmographic morphology changes induced during a hand-elevation study. Journal of Clinical Monitoring and Computing, 30(5), pp. 727-736. doi: 10.1007/s10877-015-9761-0

Cartas Ayala, A., Aghaei, M., Grueter, C., Ratnieks, F. and Reyes-Aldasoro, C. C. (2016). Behavior Analysis of Ants from Video Sequences. Paper presented at the Visual observation and analysis of Vertebrate And Insect Behavior 2016, 4 Dec 2016, Cancun, Mexico.

Villa-Arango, S., Torres Villa, R., Kyriacou, P. A. and Lucklum, R. (2016). Cavity Resonance Sensor with Disposable Analyte Container for Point of Care Testing. IEEE Sensors Journal, 16(17), pp. 6727-6732. doi: 10.1109/JSEN.2016.2584240

Foote, C. A., Castorena-Gonzalez, J. A., Ramirez-Perez, F. I., Jia, G., Hill, M. A., Reyes-Aldasoro, C. C., Sowers, J. R. and Martinez-Lemus, L. A. (2016). Arterial stiffening in western diet-fed mice is associated with increased vascular elastin, transforming growth factor-ß, and plasma neuraminidase. Frontiers in Physiology, 7, p. 285. doi: 10.3389/fphys.2016.00285

Uus, A., Liatsis, P., Slabaugh, G.G., Anagnostis, A., Roberts, S. and Twist, S. (2016). Trend Deviation Analysis for Automated Detection of Defects in GPR Data for Road Condition Surveys. Proceedings of the 23rd International Conference on Systems, Signals and Image Processing (IWSSIP 2016), doi: 10.1109/IWSSIP.2016.7502765

Pennington, K. A., Ramirez-Perez, F. I., Pollock, K. E., Talton, O. O., Foote, C. A., Reyes-Aldasoro, C. C., Wu, H-H., Ji, T., Martinez-Lemus, L. A. and Schulz, L. C. (2016). Maternal hyperleptinemia is associated with male offspring’s altered vascular function and structure in mice. PLOS One, 11(5), doi: 10.1371/journal.pone.0155377

Ramirez-Perez, F. I., Pennington, K. A., Pollock, K. E., Esangbedo, O., Foote, C. A., Reyes-Aldasoro, C. C., Wu, H-H., Ji, T., Martinez-Lemus, L. A. and Schulz, L. C. (2016). Maternal Hyperleptinemia Increases Arterial Stiffening and Alters Vasodilatoy Responses to Insulin in Adult Male Mice Offspring. The FASEB Journal, 30(1), 721.8.

Abay, T. Y. and Kyriacou, P. A. (2016). Comparison of NIRS, laser Doppler flowmetry, photoplethysmography, and pulse oximetry during vascular occlusion challenges. Physiological Measurement, 37(4), doi: 10.1088/0967-3334/37/4/503

Kather, N. J., Weis, C. A., Zöllner, F. G. and Reyes-Aldasoro, C. C. (2016). Mapping tumour tissue: quantitative maps of histological whole slide images. Oncology News, 10(6), pp. 188-190.

Sklia, D., Kyriacou, P. A. and Petros, A. J. (2016). Determining the optimal site for imaging the microcirculation in neonates using sidestream dark – field imaging. IFMBE Proceedings, 57, pp. 378-381. doi: 10.1007/978-3-319-32703-7_74

Budidha, K. (2016). In vivo investigations of photoplethysmograms and arterial oxygen saturation from the auditory canal in conditions of compromised peripheral perfusion. (Unpublished Doctoral thesis, City, University of London)

Davenport, J. J., Hickey, M., Phillips, J. P. and Kyriacou, P. A. (2016). Fiber-optic fluorescence-quenching oxygen partial pressure sensor using platinum octaethylporphyrin. Applied Optics, 55(21), pp. 5603-5609. doi: 10.1364/AO.55.005603

Davenport, J. J., Hickey, M., Phillips, J. P. and Kyriacou, P. A. (2016). Method for producing angled optical fiber tips in the laboratory. Optical Engineering, 55(2), 026120. doi: 10.1117/1.OE.55.2.026120

Green, R., Simoes, F. A., Reyes-Aldasoro, C. C., Rossor, A. M., Scoto, M., Barri, M., Greensmith, L., Muntoni, F., Reilly, M. M. and Hafezparast, M. (2016). A DYNC1H1 mutation in autosomal dominant spinal muscular atrophy shows the potential of pharmacological inhibition of histone deacetylase 6 as a treatment for disease associated cellular phenotypes. Journal Of The Peripheral Nervous System, 21(3), pp. 261-262. doi: 10.1111/jns.12181

Njoum, H. and Kyriacou, P. A. (2016). Photoplethysmography for an independent measure of pulsatile pressure under controlled flow conditions. Physiological Measurement, 38(2), 87.. doi: 10.1088/1361-6579/38/2/87

Leandrou, S., Petroudi, S., Kyriacou, P. A., Reyes-Aldasoro, C. C. and Pattichis, C. S. (2015). An overview of quantitative magnetic resonance imaging analysis studies in the assessment of alzheimer’s disease. IFMBE Proceedings, 57, pp. 281-286. doi: 10.1007/978-3-319-32703-7_56

Abay, T. and Kyriacou, P. A. (2015). Accuracy of reflectance photoplethysmography on detecting cuff-induced vascular occlusions. 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2015, pp. 861-864. doi: 10.1109/EMBC.2015.7318498

Budidha, K., Abay, T. and Kyriacou, P. A. (2015). Investigation of photoplethysmography, laser doppler flowmetry and near infrared spectroscopy during induced thermal stress. 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2015, pp. 6417-6420. doi: 10.1109/EMBC.2015.7319861

Budidha, K. and Kyriacou, P. A. (2015). Investigation of photoplethysmography and arterial blood oxygen saturation from the ear-canal and the finger under conditions of artificially induced hypothermia. Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, 2015-N, pp. 7954-7957. doi: 10.1109/EMBC.2015.7320237

Chatterjee, S., Phillips, J. P. and Kyriacou, P. A. (2015). Differential pathlength factor estimation for brain-like tissue from a single-layer Monte Carlo model. 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2015, pp. 3279-3282. doi: 10.1109/EMBC.2015.7319092

Davenport, J. J., Hickey, M., Phillips, J. P. and Kyriacou, P. A. (2015). A fiberoptic sensor for tissue carbon dioxide monitoring. 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2015, pp. 7942-7945. doi: 10.1109/EMBC.2015.7320234

McGuinness-Abdollahi, Z., Thaha, M. A., Ramsanahie, A., Ahmed, S., Kyriacou, P. A. and Phillips, J. P. (2015). Intraoperative monitoring of intestinal viability: Evaluation of a new combined sensor. Engineering in Medicine and Biology Society (EMBC), 2015 37th Annual International Conference of the IEEE, 2015, pp. 5126-5129. doi: 10.1109/EMBC.2015.7319545

Fonseca, J., Reyes-Aldasoro, C. C., O'Sullivan, C. and Coop, M. R. (2015). Experimental investigation into the primary fabric of stress transmitting particles. In: Soga, K., Kumar, K., Biscontin, G. and Kuo, M. (Eds.), Geomechanics from Micro to Macro. (pp. 1019-1024). London, UK: CRC Press. ISBN 9781138027077

Bender, S. B., Castorena-Gonzalez, J. A., Garro, M., Reyes-Aldasoro, C. C., Sowers, J. R., DeMarco, V. G. and Martinez-Lemus, L. A. (2015). Regional variation in arterial stiffening and dysfunction in western diet-induced obesity. AJP - Heart and Circulatory Physiology, 309(4), H574-H582. doi: 10.1152/ajpheart.00155.2015

Abdollahi, Z., Thaha, M. A., Ramsanahie, A., Ahmed, S., Kyriacou, P. A. and Phillips, J. P. (2015). Performance of a novel optical sensor for intraoperative assessment of intestinal viability - 'proof of principle' study. GUT, 64, A47-A48. doi: 10.1136/gutjnl-2015-309861.95

Hoffmann, E. and Reyes-Aldasoro, C. C. (2015). Automatic segmentation of centromeres, foci and delineation of chromosomes. Paper presented at the Medical Image Understanding and Analysis 2015, 15-7-2015 - 17-7-2015, University of Lincoln.

Huang, Y., Reyes-Aldasoro, C. C., Persoone, G. and Wlodkowic, D. (2015). Integrated microfluidic technology for sub-lethal and behavioral marine ecotoxicity biotests. Paper presented at the Bio-MEMS and Medical Microdevices II, 5-5-2015 - 6-5-2015, Hotel Alimara, Barcelona, Spain.

Mian, A. and Reyes-Aldasoro, C. C. (2015). Quantification of the Effects of Low Dose Radiation and its Impact on Cardiovascular Risks. Paper presented at the Quantification of the Effects of Low Dose Radiation and its Impact on Cardiovascular Risks.

Hemon, M. C. and Phillips, J. P. (2015). Comparison of foot finding methods for deriving instantaneous pulse rates from photoplethysmographic signals. Journal of Clinical Monitoring and Computing, 30(2), pp. 157-168. doi: 10.1007/s10877-015-9695-6

Abay, T. and Kyriacou, P. A. (2015). Reflectance Photoplethysmography as Non-Invasive Monitoring of Tissue Blood Perfusion.. IEEE Trans Biomed Eng, PP(99), doi: 10.1109/TBME.2015.2417863

Hickey, M., Phillips, J.P. and Kyriacou, P. A. (2015). The effect of vascular changes on the photoplethysmographic signal at different hand elevations. Physiological Measurement, 36(3), pp. 425-440. doi: 10.1088/0967-3334/36/3/425

Yin, T., Ali, F. and Reyes-Aldasoro, C. C. (2015). A Robust and Artifact Resistant Algorithm of Ultrawideband Imaging System for Breast Cancer Detection.. IEEE Trans Biomed Eng(99), doi: 10.1109/TBME.2015.2393256

Abdollahi, Z., Kyriacou, P. A. and Phillips, J. P. (2015). Evaluation of optical interference in a combined measurement system used for assessment of tissue blood flow. SPIE Proceedings, 9315(93150R), doi: 10.1117/12.2079760

Hickey, M., Phillips, J. P. and Kyriacou, P. A. (2015). Venous pooling and drainage affects photoplethysmographic signals at different vertical hand positions. Optical Diagnostics and Sensing XV: Toward Point-of-Care Diagnostics, 9332, 93320I. doi: 10.1117/12.2076732

Reyes-Aldasoro, C. C., Barri, M. and Hafezparast, M. (2015). Automatic segmentation of focal adhesions from mouse embryonic fibroblasts. In: 2015 IEEE 12th International Symposium on Biomedical Imaging (ISBI). (pp. 548-551). IEEE. ISBN 9781479923748

Blazakis, K. N., Madzvamuse, A., Reyes-Aldasoro, C. C., Styles, V. and Venkataraman, C. (2015). Whole cell tracking through the optimal control of geometric evolution laws. Journal of Computational Physics, 297, pp. 495-514. doi: 10.1016/j.jcp.2015.05.014

Fonseca, J., Reyes-Aldasoro, C. C. and Wils, L. (2015). Three-dimensional quantification of the morphology and intragranular void ratio of a shelly carbonate sand. Paper presented at the Sixth International Symposium on Deformation Characteristics of Geomaterials, 15-11-2015 - 18-11-2015, Buenos Aires.

Gama, Carolina (2015). Investigation of splanchnic perfusion utilising an intraluminal opto-electronic sensor placed in the duodenum. (Unpublished Doctoral thesis, City University London)

Kather, J. N., Marx, A., Reyes-Aldasoro, C. C., Schad, L. R., Zöllner, F. G. and Weis, C. A. (2015). Continuous representation of tumor microvessel density and detection of angiogenic hotspots in histological whole-slide images. Oncotarget, 6(22), pp. 19163-19176. doi: 10.18632/oncotarget.4383

Llado, X., Imiya, A., Mason, D., Reyes-Aldasoro, C. C., Aoki, K., Kudo, M., Zhang, Y. and Argyriou, V. (2015). Corrigendum to 'Homage to Professor Maria Petrou' [ Pattern Recognition Letters 48 (2014) 2-7].. Pattern Recognition Letters, 54(1), p. 109. doi: 10.1016/j.patrec.2015.01.006

May, J.M., Hickey, M., Triantis, I., Palazidou, E. and Kyriacou, P. A. (2015). Spectrophotometric analysis of Lithium Carbonate used for Bipolar Disorder. Biomedical Optics Express, 6(3), pp. 1067-1073. doi: 10.1364/BOE.6.001067

Miah, S., Kaparias, I. and Liatsis, P. (2015). Development and testing of a prototype instrumented bicycle model for the prevention of cyclist accidents. Paper presented at the 47th Annual Conference of the Universities’ Transport Study Group, 05-01-2015 - 07-01-2015, City University London, UK.

Shafqat, K., Langford, R. M. and Kyriacou, P. A. (2015). Estimation of instantaneous venous blood saturation using the Photoplethysmograph (PPG) waveform. Physiological Measurement, 36(10), pp. 2203-2214. doi: 10.1088/0967-3334/36/10/2203

Slabaugh, G.G. and Reyes-Aldasoro, C. C. (2015). Guest Editorial: Medical Image Understanding and Analysis. Annals of the British Machine Vision Association, 2015(1), pp. 1-2.

Solis-Lemus, J. A., Huang, Y., Wlodkovic, D. and Reyes-Aldasoro, C. C. (2015). Microfluidic environment and tracking analysis for the observation of Artemia Franciscana. Paper presented at the 26th British Machine Vision Conference, 07-09-2015 - 10-09-2015, Swansea, UK.

Yiallouras, C. (2015). Design of a 2D MRI compatible robot for performing prostate cancer treatment using therapeutic ultrasound. (Unpublished Doctoral thesis, City University London)

Llado, X., Imiya, A., Reyes-Aldasoro, C. C., Mason, D., Aoki, K., Kudo, M., Zhang, Y. and Argyriou, V. (2014). Homage to Professor Maria Petrou. Pattern Recognition Letters, 48, pp. 2-7. doi: 10.1016/j.patrec.2014.06.008

Kassanos, P., Constantinou, L., Triantis, I. and Demosthenous, A. (2014). An Integrated Analog Readout for Multi-Frequency Bioimpedance Measurements. IEEE Sensors Journal, 14(8), pp. 2792-2800. doi: 10.1109/JSEN.2014.2315963

Qassem, M. and Kyriacou, P. A. (2014). Use of reflectance near-infrared spectroscopy to investigate the effects of daily moisturizer application on skin optical response and barrier function. Journal of Biomedical Optics, 19(8), 087007. doi: 10.1117/1.JBO.19.8.087007

Kanthou, C., Dachs, G. U., Lefley, D. V., Steele, A. J., Coralli-Foxon, C., Harris, S., Greco, O., Dos Santos, S. A., Reyes-Aldasoro, C. C., English, W. R. and Tozer, G. M. (2014). Tumour cells expressing single VEGF isoforms display distinct growth, survival and migration characteristics. PLoS One, 9(8), e104015 - ?. doi: 10.1371/journal.pone.0104015

Bowyer, S., Kanthou, C. and Reyes-Aldasoro, C. C. (2014). Analysis of capillary-like structures formed by endothelial cells in a novel organotypic assay developed from heart tissue. In: Reyes-Aldasoro, C. C. and Slabaugh, G.G. (Eds.), Medical Image Understanding and Analysis 2014. (pp. 226-231). London: British Machine Vision Association. ISBN 1-901725-51-0

Stankovic, Stanislava (2014). Investigation of advanced experimental and computational techniques for behavioural characterisation of phase change materials (pcms). (Unpublished Doctoral thesis, City University London)

Budidha, K. and Kyriacou, P. A. (2014). The human ear canal: investigation of its suitability for monitoring photoplethysmographs and arterial oxygen saturation. Physiological Measurement, 35(2), pp. 111-128. doi: 10.1088/0967-3334/35/2/111

Abay, T. and Kyriacou, P. A. (2014). Investigation of Photoplethysmography and Near Infrared Spectroscopy for the Assessment of Tissue Blood Perfusion. 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), pp. 5361-5364. doi: 10.1109/EMBC.2014.6944837

Abay, T. and Kyriacou, P. A. (2014). Investigation of photoplethysmography and Near Infrared Spectroscopy for the assessment of tissue blood perfusion. Paper presented at the 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014, 26-08-2014 - 30-08-2014, Chicago, USA.

Budidha, K. and Kyriacou, P. A. (2014). Investigation of Pulse Transit Times utilizing multisite reflectance photoplethysmography under conditions of artificially induced peripheral vasoconstriction. 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), pp. 1965-1968. doi: 10.1109/EMBC.2014.6943998

  • Professor Panicos Kyriacou t: +44 (0)20 7040 8131
    Northampton Square London EC1V 0HB