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portrait of Dr Danai Dima

Dr Danai Dima

Senior Lecturer in Cognitive Neuroscience

School of Arts and Social Sciences, Department of Psychology

Contact Information


Visit Danai Dima

D206, Rhind Building

Postal Address

City, University of London
Northampton Square
United Kingdom



Dr. Dima received her Psychology degree from the Panteion University of Social and Political Sciences, Athens, Greece in 2003. She trained in Neuropsychology at the Hospital ‘Aiginiteio’, University of Athens. Following this, she completed a Masters Degree in Integrative Neuroscience at Imperial College London, UK. She was then awarded a Marie Curie Early Stage Training Fellowship for her PhD studies in Neuroscience which she completed at the Medical School Hannover, Germany in 2009. During her PhD she also trained at the Institute of Cognitive Neuroscience, University College London, UK.

Before taking up a permanent faculty position at City University London, Dr. Dima was a Senior Research Fellow at the Institute of Psychiatry, Psychology and Neuroscience, Kings College London, UK.


Dr Dima's research focuses on the study of cognition and psychosis, mainly employing neuroimaging methods and connectivity analyses in combination with genetics. Dr. Dima also co-chairs the Lifespan Working Group nested within the ENIGMA initiative.

PhD supervision

Dr Dima would welcome enquiries from potential PhD students.


Conference papers and proceedings (9)

  1. Frangou, S., Modabbernia, A., Doucet, G., Moser, D. and Dima, D. (2019). 85. Cortical Thickness and Subcortical Volume Trajectories Across the Lifespan: Data From 14,600 Healthy Individuals Aged 6-90 Years.
  2. Riaz, A., Asad, M., Arif, S.M.M.R.A., Alonso, E., Dima, D., Corr, P. … Slabaugh, G. (2018). Deep fMRI: AN end-to-end deep network for classification of fMRI data.
  3. Dima, D., de Jong, S., Breen, G., Lewis, C., Frangou, S. and Powell, T. (2018). F132. The Effect of Telomere Length and Their Polygenic Risk Scores on Emotional Brain Function and Connectivity.
  4. Anagnostopoulou, N., Alba, A., Gaete, J., Dima, D. and Kyriakopoulos, M. (2018). Prevalence of psychotic symptoms in children needing inpatient care: Relationship to diagnosis.
  5. Zhu, D., Riedel, B.C., Jahanshad, N., Groenewold, N.A., Stein, D.J., Gotlib, I.H. … Thompson, P.M. (2017). Classification of major depressive disorder via multi-site weighted LASSO model.
  6. Riaz, A., Asad, M., Al-Arif, S.M.M.R., Alonso, E., Dima, D., Corr, P. … Slabaugh, G. (2017). FCNet: A convolutional neural network for calculating functional connectivity from functional MRI.
  7. Zhu, D., Riedel, B.C., Jahanshad, N., Groenewold, N.A., Stein, D.J., Gotlib, I.H. … Thompson, P.M. (2017). Classification of Major Depressive Disorder via Multi-site Weighted LASSO Model.
  8. Frangou, S., Dima, D. and Grp, E.N.I.G.M.A.L.W. (2016). Brain Morphological Changes Across the Lifespan.
  9. Frangou, S., Dima, D. and Grp, E.N.I.G.M.A.L.W. (2016). Age-related Changes in Subcortical Volumes in Healthy Individuals Aged 2-92 Years: Brain Region Specific Growth Curves.

Internet publication

  1. Dima, D., Young, D. and Duggan, M. (2017). Three reasons to think twice about mapping the brain. The Conversation.

Journal articles (60)

  1. Turkheimer, F.E., Althubaity, N., Schubert, J., Nettis, M.A., Cousins, O., Dima, D. … Veronese, M. (2021). Increased serum peripheral C-reactive protein is associated with reduced brain barriers permeability of TSPO radioligands in healthy volunteers and depressed patients: implications for inflammation and depression. Brain, Behavior, and Immunity, 91, pp. 487–497. doi:10.1016/j.bbi.2020.10.025.
  2. Thompson, P.M., Jahanshad, N., Ching, C.R.K., Salminen, L.E., Thomopoulos, S.I., Bright, J. … Francks, C. (2020). ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries. Translational Psychiatry, 10(1). doi:10.1038/s41398-020-0705-1.
  3. Modinos, G., Allen, P., Zugman, A., Dima, D., Azis, M., Samson, C. … McGuire, P. (2020). Neural Circuitry of Novelty Salience Processing in Psychosis Risk: Association with Clinical Outcome. Schizophrenia Bulletin, 46(3), pp. 670–679. doi:10.1093/schbul/sbz089.
  4. Tozzi, L., Garczarek, L., Janowitz, D., Stein, D.J., Wittfeld, K., Dobrowolny, H. … Frodl, T. (2020). Interactive impact of childhood maltreatment, depression, and age on cortical brain structure: Mega-analytic findings from a large multi-site cohort. Psychological Medicine, 50(6), pp. 1020–1031. doi:10.1017/S003329171900093X.
  5. Galitzer, H., Anagnostopoulou, N., Alba, A., Gaete, J., Dima, D. and Kyriakopoulos, M. (2020). Functional outcomes and patient satisfaction following inpatient treatment for childhood-onset schizophrenia spectrum disorders vs non-psychotic disorders in children in the United Kingdom. Early Intervention in Psychiatry. doi:10.1111/eip.12973.
  6. Han, L.K.M., Dinga, R., Hahn, T., Ching, C.R.K., Eyler, L.T., Aftanas, L. … Fullerton, J.M. (2020). Brain aging in major depressive disorder: results from the ENIGMA major depressive disorder working group. Molecular Psychiatry. doi:10.1038/s41380-020-0754-0.
  7. Ioakeimidis, V., Haenschel, C., Yarrow, K., Kyriakopoulos, M. and Dima, D. (2020). A Meta-analysis of Structural and Functional Brain Abnormalities in Early-Onset Schizophrenia. Schizophrenia Bulletin Open, 1(1). doi:10.1093/schizbullopen/sgaa016.
  8. Ching, C.R.K., Hibar, D.P., Gurholt, T.P., Nunes, A., Thomopoulos, S.I., Abé, C. … Sim, K. (2020). What we learn about bipolar disorder from large-scale neuroimaging: Findings and future directions from the ENIGMA Bipolar Disorder Working Group. Human Brain Mapping. doi:10.1002/hbm.25098.
  9. Patel, Y., Parker, N., Shin, J., Howard, D., French, L., Thomopoulos, S.I. … Guerrero-Pedraza, A. (2020). Virtual Histology of Cortical Thickness and Shared Neurobiology in 6 Psychiatric Disorders. JAMA Psychiatry. doi:10.1001/jamapsychiatry.2020.2694.
  10. Wierenga, L.M., Doucet, G.E., Dima, D., Agartz, I., Aghajani, M., Akudjedu, T.N. … McPhilemy, G. (2020). Greater male than female variability in regional brain structure across the lifespan. Human Brain Mapping. doi:10.1002/hbm.25204.
  11. Smeeth, D.M., Dima, D., Jones, L., Jones, I., Craddock, N., Owen, M.J. … Powell, T.R. (2019). Polygenic risk for circulating reproductive hormone levels and their influence on hippocampal volume and depression susceptibility. Psychoneuroendocrinology, 106, pp. 284–292. doi:10.1016/j.psyneuen.2019.04.011.
  12. Dezhina, Z., Ranlund, S., Kyriakopoulos, M., Williams, S.C.R. and Dima, D. (2019). A systematic review of associations between functional MRI activity and polygenic risk for schizophrenia and bipolar disorder. Brain Imaging and Behavior, 13(3), pp. 862–877. doi:10.1007/s11682-018-9879-z.
  13. Powell, T.R., De Jong, S., Breen, G., Lewis, C.M. and Dima, D. (2019). Telomere length as a predictor of emotional processing in the brain. Human Brain Mapping, 40(6), pp. 1750–1759. doi:10.1002/hbm.24487.
  14. van Erp, T.G.M., Walton, E., Hibar, D.P., Schmaal, L., Jiang, W., Glahn, D.C. … Orhan, F. (2019). Reply to: New Meta- and Mega-analyses of Magnetic Resonance Imaging Findings in Schizophrenia: Do They Really Increase Our Knowledge About the Nature of the Disease Process? Biological Psychiatry, 85(7). doi:10.1016/j.biopsych.2018.10.003.
  15. Goikolea, J.M., Dima, D., Landín-Romero, R., Torres, I., Delvecchio, G., Valentí, M. … Vieta, E. (2019). Multimodal Brain Changes in First-Episode Mania: A Voxel-Based Morphometry, Functional Magnetic Resonance Imaging, and Connectivity Study. Schizophrenia Bulletin, 45(2), pp. 464–473. doi:10.1093/schbul/sby047.
  16. Coutts, F., Palmos, A.B., Duarte, R.R.R., de Jong, S., Lewis, C.M., Dima, D. … Powell, T.R. (2019). The polygenic nature of telomere length and the anti-ageing properties of lithium. Neuropsychopharmacology, 44(4), pp. 757–765. doi:10.1038/s41386-018-0289-0.
  17. De Kovel, C.G.F., Aftanas, L., Aleman, A., Alexander-Bloch, A.F., Baune, B.T., Brack, I. … Francks, C. (2019). No alterations of brain structural asymmetry in major depressive disorder: An ENIGMA consortium analysis. American Journal of Psychiatry, 176(12), pp. 1039–1049. doi:10.1176/appi.ajp.2019.18101144.
  18. van Erp, T.G.M., Walton, E., Hibar, D.P., Schmaal, L., Jiang, W., Glahn, D.C. … Orhan, F. (2018). Cortical Brain Abnormalities in 4474 Individuals With Schizophrenia and 5098 Control Subjects via the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA) Consortium. Biological Psychiatry, 84(9), pp. 644–654. doi:10.1016/j.biopsych.2018.04.023.
  19. Roberts, R.E., Ahmad, H., Patel, M., Dima, D., Ibitoye, R., Sharif, M. … Bronstein, A.M. (2018). An fMRI study of visuo-vestibular interactions following vestibular neuritis. NeuroImage: Clinical, 20, pp. 1010–1017. doi:10.1016/j.nicl.2018.10.007.
  20. Hibar, D.P., Westlye, L.T., Doan, N.T., Jahanshad, N., Cheung, J.W., Ching, C.R.K. … Lawrence, N.S. (2018). Cortical abnormalities in bipolar disorder: An MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group. Molecular Psychiatry, 23(4), pp. 932–942. doi:10.1038/mp.2017.73.
  21. Worker, A., Dima, D., Combes, A., Crum, W.R., Streffer, J., Einstein, S. … O'daly, O. (2018). Test–retest reliability and longitudinal analysis of automated hippocampal subregion volumes in healthy ageing and Alzheimer's disease populations. Human Brain Mapping, 39(4), pp. 1743–1754. doi:10.1002/hbm.23948.
  22. Braeutigam, S., Dima, D., Frangou, S. and James, A. (2018). Dissociable auditory mismatch response and connectivity patterns in adolescents with schizophrenia and adolescents with bipolar disorder with psychosis: A magnetoencephalography study. Schizophrenia Research, 193, pp. 313–318. doi:10.1016/j.schres.2017.07.048.
  23. Powell, T.R., Dima, D., Frangou, S. and Breen, G. (2018). Telomere length and bipolar disorder. Neuropsychopharmacology, 43(2), pp. 445–453. doi:10.1038/npp.2017.125.
  24. Pezzoli, S., Emsell, L., Yip, S.W., Dima, D., Giannakopoulos, P., Zarei, M. … Kempton, M.J. (2018). Meta-analysis of regional white matter volume in bipolar disorder with replication in an independent sample using coordinates, T-maps, and individual MRI data. Neuroscience and Biobehavioral Reviews, 84, pp. 162–170. doi:10.1016/j.neubiorev.2017.11.005.
  25. Ranlund, S., Rosa, M.J., de Jong, S., Cole, J.H., Kyriakopoulos, M., Fu, C.H.Y. … Dima, D. (2018). Associations between polygenic risk scores for four psychiatric illnesses and brain structure using multivariate pattern recognition. NeuroImage: Clinical, 20, pp. 1026–1036. doi:10.1016/j.nicl.2018.10.008.
  26. Moser, D.A., Doucet, G.E., Ing, A., Dima, D., Schumann, G., Bilder, R.M. … Frangou, S. (2017). An integrated brain-behavior model for working memory. Molecular psychiatry. doi:10.1038/mp.2017.247.
  27. Harrison, R.N.S., Gaughran, F., Murray, R.M., Lee, S.H., Cano, J.P., Dempster, D. … Breen, G. (2017). Development of multivariable models to predict change in Body Mass Index within a clinical trial population of psychotic individuals. Scientific Reports, 7(1). doi:10.1038/s41598-017-15137-7.
  28. Roberts, R.E., Ahmad, H., Arshad, Q., Patel, M., Dima, D., Leech, R. … Bronstein, A.M. (2017). Functional neuroimaging of visuo-vestibular interaction. Brain Structure and Function, 222(5), pp. 2329–2343. doi:10.1007/s00429-016-1344-4.
  29. Kaushik, A., Papachristou, E., Dima, D., Fewings, S., Kostaki, E., Ploubidis, G.B. … Kyriakopoulos, M. (2017). Measuring stigma in children receiving mental health treatment: Validation of the Paediatric Self-Stigmatization Scale (PaedS). European Psychiatry, 43, pp. 1–8. doi:10.1016/j.eurpsy.2017.01.004.
  30. Thompson, P.M., Dennis, E.L., Gutman, B.A., Hibar, D.P., Jahanshad, N., Kelly, S. … Ye, J. (2017). ENIGMA and the individual: Predicting factors that affect the brain in 35 countries worldwide. NeuroImage, 145, pp. 389–408. doi:10.1016/j.neuroimage.2015.11.057.
  31. Frangou, S., Dima, D. and Jogia, J. (2017). Towards person-centered neuroimaging markers for resilience and vulnerability in Bipolar Disorder. NeuroImage, 145, pp. 230–237. doi:10.1016/j.neuroimage.2016.08.066.
  32. Hibar, D.P., Westlye, L.T., Van Erp, T.G.M., Rasmussen, J., Leonardo, C.D., Faskowitz, J. … Andreassen, O.A. (2016). Subcortical volumetric abnormalities in bipolar disorder. Molecular Psychiatry, 21(12), pp. 1710–1716. doi:10.1038/mp.2015.227.
  33. Mason, L., Peters, E.R., Dima, D., Williams, S.C. and Kumari, V. (2016). Cognitive behavioral therapy normalizes functional connectivity for social threat in psychosis. Schizophrenia Bulletin, 42(3), pp. 684–692. doi:10.1093/schbul/sbv153.
  34. Dima, D., Roberts, R.E. and Frangou, S. (2016). Connectomic markers of disease expression, genetic risk and resilience in bipolar disorder. Translational Psychiatry, 6. doi:10.1038/tp.2015.193.
  35. Harrison, R.N.S., Murray, R.M., Lee, S.H., Cano, J.P., Dempster, D., Curtis, C.J. … De Jong, S. (2016). Gene-expression analysis of clozapine treatment in whole blood of patients with psychosis. Psychiatric Genetics, 26(5), pp. 211–217. doi:10.1097/YPG.0000000000000140.
  36. Dima, D., de Jong, S., Breen, G. and Frangou, S. (2016). The polygenic risk for bipolar disorder influences brain regional function relating to visual and default state processing of emotional information. NeuroImage: Clinical, 12, pp. 838–844. doi:10.1016/j.nicl.2016.10.022.
  37. Dima, D., Friston, K.J., Stephan, K.E. and Frangou, S. (2015). Neuroticism and conscientiousness respectively constrain and facilitate short-term plasticity within the working memory neural network. Human Brain Mapping, 36(10), pp. 4158–4163. doi:10.1002/hbm.22906.
  38. Dima, D. and Breen, G. (2015). Polygenic risk scores in imaging genetics: Usefulness and applications. Journal of Psychopharmacology, 29(8), pp. 867–871. doi:10.1177/0269881115584470.
  39. Mucci, A., Dima, D., Soricelli, A., Volpe, U., Bucci, P., Frangou, S. … Maj, M. (2015). Is avolition in schizophrenia associated with a deficit of dorsal caudate activity? A functional magnetic resonance imaging study during reward anticipation and feedback. Psychological Medicine, 45(8), pp. 1765–1778. doi:10.1017/S0033291714002943.
  40. Delvecchio, G., Dima, D. and Frangou, S. (2015). The effect of ANK3 bipolar-risk polymorphisms on the working memory circuitry differs between loci and according to risk-status for bipolar disorder. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics, 168(3), pp. 188–196. doi:10.1002/ajmg.b.32294.
  41. Schneider, C., Papachristou, E., Wimberley, T., Gasse, C., Dima, D., MacCabe, J.H. … Frangou, S. (2015). Clozapine use in childhood and adolescent schizophrenia: A nationwide population-based study. European Neuropsychopharmacology, 25(6), pp. 857–863. doi:10.1016/j.euroneuro.2015.02.003.
  42. Samartzis, L., Dima, D., Fusar-Poli, P. and Kyriakopoulos, M. (2014). White matter alterations in early stages of schizophrenia: A systematic review of diffusion tensor imaging studies. Journal of Neuroimaging, 24(2), pp. 101–110. doi:10.1111/j.1552-6569.2012.00779.x.
  43. Schulz, K.P., Bédard, A.C.V., Fan, J., Clerkin, S.M., Dima, D., Newcorn, J.H. … Halperin, J.M. (2014). Emotional bias of cognitive control in adults with childhood attention-deficit/hyperactivity disorder. NeuroImage: Clinical, 5, pp. 1–9. doi:10.1016/j.nicl.2014.05.016.
  44. Thompson, P.M., Stein, J.L., Medland, S.E., Hibar, D.P., Vasquez, A.A., Renteria, M.E. … Grabe, H.J. (2014). The ENIGMA Consortium: Large-scale collaborative analyses of neuroimaging and genetic data. Brain Imaging and Behavior, 8(2), pp. 153–182. doi:10.1007/s11682-013-9269-5.
  45. Dima, D., Jogia, J. and Frangou, S. (2014). Dynamic causal modeling of load-dependent modulation of effective connectivity within the verbal working memory network. Human Brain Mapping, 35(7), pp. 3025–3035. doi:10.1002/hbm.22382.
  46. Morandotti, N., Dima, D., Jogia, J., Frangou, S., Sala, M., Vidovich, G.Z.D. … Brambilla, P. (2013). Childhood abuse is associated with structural impairment in the ventrolateral prefrontal cortex and aggressiveness in patients with borderline personality disorder. Psychiatry Research - Neuroimaging, 213(1), pp. 18–23. doi:10.1016/j.pscychresns.2013.02.002.
  47. Brambilla, P., Perlini, C., Bellani, M., Tomelleri, L., Ferro, A., Cerruti, S. … Frangou, S. (2013). Increased salience of gains versus decreased associative learning differentiate bipolar disorder from schizophrenia during incentive decision making. Psychological Medicine, 43(3), pp. 571–580. doi:10.1017/S0033291712001304.
  48. Dima, D., Jogia, J., Collier, D., Vassos, E., Burdick, K.E. and Frangou, S. (2013). Independent modulation of engagement and connectivity of the facial network during affect processing by CACNA1C and ANK3 risk genes for bipolar disorder. JAMA Psychiatry, 70(12), pp. 1303–1311. doi:10.1001/jamapsychiatry.2013.2099.
  49. Jogia, J., Dima, D., Kumari, V. and Frangou, S. (2012). Frontopolar cortical inefficiency may underpin reward and working memory dysfunction in bipolar disorder. World Journal of Biological Psychiatry, 13(8), pp. 605–615. doi:10.3109/15622975.2011.585662.
  50. Sugranyes, G., Kyriakopoulos, M., Dima, D., O'Muircheartaigh, J., Corrigall, R., Pendelbury, G. … Frangou, S. (2012). Multimodal analyses identify linked functional and white matter abnormalities within the working memory network in schizophrenia. Schizophrenia Research, 138(2-3), pp. 136–142. doi:10.1016/j.schres.2012.03.011.
  51. Jogia, J., Dima, D. and Frangou, S. (2012). Sex differences in bipolar disorder: A review of neuroimaging findings and new evidence. Bipolar Disorders, 14(4), pp. 461–471. doi:10.1111/j.1399-5618.2012.01014.x.
  52. Dima, D., Frangou, S., Burge, L., Braeutigam, S. and James, A.C. (2012). Abnormal intrinsic and extrinsic connectivity within the magnetic mismatch negativity brain network in schizophrenia: A preliminary study. Schizophrenia Research, 135(1-3), pp. 23–27. doi:10.1016/j.schres.2011.12.024.
  53. Kyriakopoulos, M., Dima, D., Roiser, J.P., Corrigall, R., Barker, G.J. and Frangou, S. (2012). Abnormal functional activation and connectivity in the working memory network in early-onset schizophrenia. Journal of the American Academy of Child and Adolescent Psychiatry, 51(9), pp. 911–920. doi:10.1016/j.jaac.2012.06.020.
  54. Neufeld, J., Sinke, C., Dillo, W., Emrich, H.M., Szycik, G.R., Dima, D. … Zedler, M. (2012). The neural correlates of coloured music: A functional MRI investigation of auditory-visual synaesthesia. Neuropsychologia, 50(1), pp. 85–89. doi:10.1016/j.neuropsychologia.2011.11.001.
  55. Dima, D., Stephan, K.E., Roiser, J.P., Friston, K.J. and Frangou, S. (2011). Effective connectivity during processing of facial affect: Evidence for multiple parallel pathways. Journal of Neuroscience, 31(40), pp. 14378–14385. doi:10.1523/JNEUROSCI.2400-11.2011.
  56. Pompei, F., Dima, D., Rubia, K., Kumari, V. and Frangou, S. (2011). Dissociable functional connectivity changes during the Stroop task relating to risk, resilience and disease expression in bipolar disorder. NeuroImage, 57(2), pp. 576–582. doi:10.1016/j.neuroimage.2011.04.055.
  57. Dima, D., Dillo, W., Bonnemann, C., Emrich, H.M. and Dietrich, D.E. (2011). Reduced P300 and P600 amplitude in the hollow-mask illusion in patients with schizophrenia. Psychiatry Research - Neuroimaging, 191(2), pp. 145–151. doi:10.1016/j.pscychresns.2010.09.015.
  58. Dima, D., Dietrich, D.E., Dillo, W. and Emrich, H.M. (2010). Impaired top-down processes in schizophrenia: A DCM study of ERPs. NeuroImage, 52(3), pp. 824–832. doi:10.1016/j.neuroimage.2009.12.086.
  59. Dima, D., Roiser, J.P., Dietrich, D.E., Bonnemann, C., Lanfermann, H., Emrich, H.M. … Dillo, W. (2009). Understanding why patients with schizophrenia do not perceive the hollow-mask illusion using dynamic causal modelling. NeuroImage, 46(4), pp. 1180–1186. doi:10.1016/j.neuroimage.2009.03.033.
  60. Dima, D., Papachristou, E., Modabbernia, A., Doucet, G.E., Agartz, I., Aghajani, M. … Frangou, S. Subcortical Volume Trajectories across the Lifespan: Data from 18,605 healthy individuals aged 3-90 years. . doi:10.1101/2020.05.05.079475.


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PS1009 Psychology at City

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PS2004 Biological Psychology