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portrait of Dr Danai Dima

Dr Danai Dima

Senior Lecturer in Cognitive Neuroscience

School of Arts and Social Sciences, Department of Psychology

Contact Information

Contact

Visit Danai Dima

D206, Rhind Building

Postal Address

City, University of London
Northampton Square
London
EC1V 0HB
United Kingdom

About

Overview

Dr. Dima received her Psychology degree from the Panteion University of Social and Political Sciences, Athens, Greece in 2003. She trained in Neuropsychology at the Hospital ‘Aiginiteio’, University of Athens. Following this, she completed a Masters Degree in Integrative Neuroscience at Imperial College London, UK. She was then awarded a Marie Curie Early Stage Training Fellowship for her PhD studies in Neuroscience which she completed at the Medical School Hannover, Germany in 2009. During her PhD she also trained at the Institute of Cognitive Neuroscience, University College London, UK.

Before taking up a permanent faculty position at City University London, Dr. Dima was a Senior Research Fellow at the Institute of Psychiatry, Psychology and Neuroscience, Kings College London, UK.

Research

Dr Dima's research focuses on the study of cognition and psychosis, mainly employing neuroimaging methods and connectivity analyses in combination with genetics. Dr. Dima also co-chairs the Lifespan Working Group nested within the ENIGMA initiative.

PhD supervision

Dr Dima would welcome enquiries from potential PhD students.

Publications

Conference papers and proceedings (7)

  1. Riaz, A., Asad, M., Arif, S.M.M.R.A., Alonso, E., Dima, D., Corr, P. … Slabaugh, G. (2018). Deep fMRI: AN end-to-end deep network for classification of fMRI data.
  2. Dima, D., de Jong, S., Breen, G., Lewis, C., Frangou, S. and Powell, T. (2018). The Effect of Telomere Length and Their Polygenic Risk Scores on Emotional Brain Function and Connectivity.
  3. Zhu, D., Riedel, B.C., Jahanshad, N., Groenewold, N.A., Stein, D.J., Gotlib, I.H. … Thompson, P.M. (2017). Classification of major depressive disorder via multi-site weighted LASSO model.
  4. Riaz, A., Asad, M., Al-Arif, S.M.M.R., Alonso, E., Dima, D., Corr, P. … Slabaugh, G. (2017). FCNet: A convolutional neural network for calculating functional connectivity from functional MRI.
  5. Zhu, D., Riedel, B.C., Jahanshad, N., Groenewold, N.A., Stein, D.J., Gotlib, I.H. … Thompson, P.M. (2017). Classification of Major Depressive Disorder via Multi-site Weighted LASSO Model.
  6. Frangou, S., Dima, D. and Grp, E.N.I.G.M.A.L.W. (2016). Brain Morphological Changes Across the Lifespan.
  7. Frangou, S., Dima, D. and Grp, E.N.I.G.M.A.L.W. (2016). Age-related Changes in Subcortical Volumes in Healthy Individuals Aged 2-92 Years: Brain Region Specific Growth Curves.

Internet publication

  1. Dima, D., Young, D. and Duggan, M. (2017). Three reasons to think twice about mapping the brain. The Conversation.

Journal articles (42)

  1. Dezhina, Z., Ranlund, S., Kyriakopoulos, M., Williams, S.C.R. and Dima, D. (2018). A systematic review of associations between functional MRI activity and polygenic risk for schizophrenia and bipolar disorder. Brain Imaging and Behavior pp. 1–16. doi:10.1007/s11682-018-9879-z.
  2. van Erp, T.G., Walton, E., Hibar, D.P., Schmaal, L., Jiang, W., Glahn, D.C. … Orhan, F. (2018). Cortical Brain Abnormalities in 4474 Individuals With Schizophrenia and 5098 Control Subjects via the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA) Consortium. Biological Psychiatry. doi:10.1016/j.biopsych.2018.04.023.
  3. Goikolea, J.M., Dima, D., Landín-Romero, R., Torres, I., DelVecchio, G., Valentí, M. … Vieta, E. (2018). Multimodal Brain Changes in First-Episode Mania: A Voxel-Based Morphometry, Functional Magnetic Resonance Imaging, and Connectivity Study. Schizophrenia bulletin. doi:10.1093/schbul/sby047.
  4. Hibar, D.P., Westlye, L.T., Doan, N.T., Jahanshad, N., Cheung, J.W., Ching, C.R.K. … Nery, F.G. (2018). Cortical abnormalities in bipolar disorder: An MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group. Molecular Psychiatry, 23(4), pp. 932–942. doi:10.1038/mp.2017.73.
  5. Worker, A., Dima, D., Combes, A., Crum, W.R., Streffer, J., Einstein, S. … O'daly, O. (2018). Test–retest reliability and longitudinal analysis of automated hippocampal subregion volumes in healthy ageing and Alzheimer's disease populations. Human Brain Mapping, 39(4), pp. 1743–1754. doi:10.1002/hbm.23948.
  6. Braeutigam, S., Dima, D., Frangou, S. and James, A. (2018). Dissociable auditory mismatch response and connectivity patterns in adolescents with schizophrenia and adolescents with bipolar disorder with psychosis: A magnetoencephalography study. Schizophrenia Research, 193, pp. 313–318. doi:10.1016/j.schres.2017.07.048.
  7. Pezzoli, S., Emsell, L., Yip, S.W., Dima, D., Giannakopoulos, P., Zarei, M. … Kempton, M.J. (2018). Meta-analysis of regional white matter volume in bipolar disorder with replication in an independent sample using coordinates, T-maps, and individual MRI data. Neuroscience and Biobehavioral Reviews, 84, pp. 162–170. doi:10.1016/j.neubiorev.2017.11.005.
  8. Moser, D.A., Doucet, G.E., Ing, A., Dima, D., Schumann, G., Bilder, R.M. … Frangou, S. (2017). An integrated brain-behavior model for working memory. Molecular psychiatry. doi:10.1038/mp.2017.247.
  9. Harrison, R.N.S., Gaughran, F., Murray, R.M., Lee, S.H., Cano, J.P., Dempster, D. … Breen, G. (2017). Development of multivariable models to predict change in Body Mass Index within a clinical trial population of psychotic individuals. Scientific Reports, 7(1). doi:10.1038/s41598-017-15137-7.
  10. Roberts, R.E., Ahmad, H., Arshad, Q., Patel, M., Dima, D., Leech, R. … Bronstein, A.M. (2017). Functional neuroimaging of visuo-vestibular interaction. Brain Structure and Function, 222(5), pp. 2329–2343. doi:10.1007/s00429-016-1344-4.
  11. Kaushik, A., Papachristou, E., Dima, D., Fewings, S., Kostaki, E., Ploubidis, G.B. … Kyriakopoulos, M. (2017). Measuring stigma in children receiving mental health treatment: Validation of the Paediatric Self-Stigmatization Scale (PaedS). European Psychiatry, 43, pp. 1–8. doi:10.1016/j.eurpsy.2017.01.004.
  12. Thompson, P.M., Dennis, E.L., Gutman, B.A., Hibar, D.P., Jahanshad, N., Kelly, S. … Schmaal, L. (2017). ENIGMA and the individual: Predicting factors that affect the brain in 35 countries worldwide. NeuroImage, 145, pp. 389–408. doi:10.1016/j.neuroimage.2015.11.057.
  13. Frangou, S., Dima, D. and Jogia, J. (2017). Towards person-centered neuroimaging markers for resilience and vulnerability in Bipolar Disorder. NeuroImage, 145, pp. 230–237. doi:10.1016/j.neuroimage.2016.08.066.
  14. Powell, T.R., Dima, D., Frangou, S. and Breen, G. (2017). Telomere length and bipolar disorder. Neuropsychopharmacology, 43(2), pp. 445–453. doi:10.1038/npp.2017.125.
  15. Hibar, D.P., Westlye, L.T., Van Erp, T.G.M., Rasmussen, J., Leonardo, C.D., Faskowitz, J. … Thompson, P.M. (2016). Subcortical volumetric abnormalities in bipolar disorder. Molecular Psychiatry, 21(12), pp. 1710–1716. doi:10.1038/mp.2015.227.
  16. Mason, L., Peters, E.R., Dima, D., Williams, S.C. and Kumari, V. (2016). Cognitive behavioral therapy normalizes functional connectivity for social threat in psychosis. Schizophrenia Bulletin, 42(3), pp. 684–692. doi:10.1093/schbul/sbv153.
  17. Dima, D., Roberts, R.E. and Frangou, S. (2016). Connectomic markers of disease expression, genetic risk and resilience in bipolar disorder. Translational Psychiatry, 6. doi:10.1038/tp.2015.193.
  18. Harrison, R.N.S., Murray, R.M., Lee, S.H., Cano, J.P., Dempster, D., Curtis, C.J. … De Jong, S. (2016). Gene-expression analysis of clozapine treatment in whole blood of patients with psychosis. Psychiatric Genetics, 26(5), pp. 211–217. doi:10.1097/YPG.0000000000000140.
  19. Dima, D., de Jong, S., Breen, G. and Frangou, S. (2016). The polygenic risk for bipolar disorder influences brain regional function relating to visual and default state processing of emotional information. NeuroImage: Clinical, 12, pp. 838–844. doi:10.1016/j.nicl.2016.10.022.
  20. Dima, D., Friston, K.J., Stephan, K.E. and Frangou, S. (2015). Neuroticism and conscientiousness respectively constrain and facilitate short-term plasticity within the working memory neural network. Human Brain Mapping, 36(10), pp. 4158–4163. doi:10.1002/hbm.22906.
  21. Dima, D. and Breen, G. (2015). Polygenic risk scores in imaging genetics: Usefulness and applications. Journal of Psychopharmacology, 29(8), pp. 867–871. doi:10.1177/0269881115584470.
  22. Mucci, A., Dima, D., Soricelli, A., Volpe, U., Bucci, P., Frangou, S. … Maj, M. (2015). Is avolition in schizophrenia associated with a deficit of dorsal caudate activity? A functional magnetic resonance imaging study during reward anticipation and feedback. Psychological Medicine, 45(8), pp. 1765–1778. doi:10.1017/S0033291714002943.
  23. Delvecchio, G., Dima, D. and Frangou, S. (2015). The effect of ANK3 bipolar-risk polymorphisms on the working memory circuitry differs between loci and according to risk-status for bipolar disorder. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics, 168(3), pp. 188–196. doi:10.1002/ajmg.b.32294.
  24. Schneider, C., Papachristou, E., Wimberley, T., Gasse, C., Dima, D., MacCabe, J.H. … Frangou, S. (2015). Clozapine use in childhood and adolescent schizophrenia: A nationwide population-based study. European Neuropsychopharmacology, 25(6), pp. 857–863. doi:10.1016/j.euroneuro.2015.02.003.
  25. Samartzis, L., Dima, D., Fusar-Poli, P. and Kyriakopoulos, M. (2014). White matter alterations in early stages of schizophrenia: A systematic review of diffusion tensor imaging studies. Journal of Neuroimaging, 24(2), pp. 101–110. doi:10.1111/j.1552-6569.2012.00779.x.
  26. Dima, D., Jogia, J. and Frangou, S. (2014). Dynamic causal modeling of load-dependent modulation of effective connectivity within the verbal working memory network. Human Brain Mapping, 35(7), pp. 3025–3035. doi:10.1002/hbm.22382.
  27. Thompson, P.M., Stein, J.L., Medland, S.E., Hibar, D.P., Vasquez, A.A., Renteria, M.E. … Djurovic, S. (2014). The ENIGMA Consortium: Large-scale collaborative analyses of neuroimaging and genetic data. Brain Imaging and Behavior, 8(2), pp. 153–182. doi:10.1007/s11682-013-9269-5.
  28. Schulz, K.P., Bédard, A.C.V., Fan, J., Clerkin, S.M., Dima, D., Newcorn, J.H. … Halperin, J.M. (2014). Emotional bias of cognitive control in adults with childhood attention-deficit/hyperactivity disorder. NeuroImage: Clinical, 5, pp. 1–9. doi:10.1016/j.nicl.2014.05.016.
  29. Morandotti, N., Dima, D., Jogia, J., Frangou, S., Sala, M., Vidovich, G.Z.D. … Brambilla, P. (2013). Childhood abuse is associated with structural impairment in the ventrolateral prefrontal cortex and aggressiveness in patients with borderline personality disorder. Psychiatry Research - Neuroimaging, 213(1), pp. 18–23. doi:10.1016/j.pscychresns.2013.02.002.
  30. Brambilla, P., Perlini, C., Bellani, M., Tomelleri, L., Ferro, A., Cerruti, S. … Frangou, S. (2013). Increased salience of gains versus decreased associative learning differentiate bipolar disorder from schizophrenia during incentive decision making. Psychological Medicine, 43(3), pp. 571–580. doi:10.1017/S0033291712001304.
  31. Dima, D., Jogia, J., Collier, D., Vassos, E., Burdick, K.E. and Frangou, S. (2013). Independent modulation of engagement and connectivity of the facial network during affect processing by CACNA1C and ANK3 risk genes for bipolar disorder. JAMA Psychiatry, 70(12), pp. 1303–1311. doi:10.1001/jamapsychiatry.2013.2099.
  32. Jogia, J., Dima, D., Kumari, V. and Frangou, S. (2012). Frontopolar cortical inefficiency may underpin reward and working memory dysfunction in bipolar disorder. World Journal of Biological Psychiatry, 13(8), pp. 605–615. doi:10.3109/15622975.2011.585662.
  33. Kyriakopoulos, M., Dima, D., Roiser, J.P., Corrigall, R., Barker, G.J. and Frangou, S. (2012). Abnormal functional activation and connectivity in the working memory network in early-onset schizophrenia. Journal of the American Academy of Child and Adolescent Psychiatry, 51(9), pp. 911–920. doi:10.1016/j.jaac.2012.06.020.
  34. Sugranyes, G., Kyriakopoulos, M., Dima, D., O'Muircheartaigh, J., Corrigall, R., Pendelbury, G. … Frangou, S. (2012). Multimodal analyses identify linked functional and white matter abnormalities within the working memory network in schizophrenia. Schizophrenia Research, 138(2-3), pp. 136–142. doi:10.1016/j.schres.2012.03.011.
  35. Jogia, J., Dima, D. and Frangou, S. (2012). Sex differences in bipolar disorder: A review of neuroimaging findings and new evidence. Bipolar Disorders, 14(4), pp. 461–471. doi:10.1111/j.1399-5618.2012.01014.x.
  36. Dima, D., Frangou, S., Burge, L., Braeutigam, S. and James, A.C. (2012). Abnormal intrinsic and extrinsic connectivity within the magnetic mismatch negativity brain network in schizophrenia: A preliminary study. Schizophrenia Research, 135(1-3), pp. 23–27. doi:10.1016/j.schres.2011.12.024.
  37. Neufeld, J., Sinke, C., Dillo, W., Emrich, H.M., Szycik, G.R., Dima, D. … Zedler, M. (2012). The neural correlates of coloured music: A functional MRI investigation of auditory-visual synaesthesia. Neuropsychologia, 50(1), pp. 85–89. doi:10.1016/j.neuropsychologia.2011.11.001.
  38. Dima, D., Stephan, K.E., Roiser, J.P., Friston, K.J. and Frangou, S. (2011). Effective connectivity during processing of facial affect: Evidence for multiple parallel pathways. Journal of Neuroscience, 31(40), pp. 14378–14385. doi:10.1523/JNEUROSCI.2400-11.2011.
  39. Pompei, F., Dima, D., Rubia, K., Kumari, V. and Frangou, S. (2011). Dissociable functional connectivity changes during the Stroop task relating to risk, resilience and disease expression in bipolar disorder. NeuroImage, 57(2), pp. 576–582. doi:10.1016/j.neuroimage.2011.04.055.
  40. Dima, D., Dillo, W., Bonnemann, C., Emrich, H.M. and Dietrich, D.E. (2011). Reduced P300 and P600 amplitude in the hollow-mask illusion in patients with schizophrenia. Psychiatry Research - Neuroimaging, 191(2), pp. 145–151. doi:10.1016/j.pscychresns.2010.09.015.
  41. Dima, D., Dietrich, D.E., Dillo, W. and Emrich, H.M. (2010). Impaired top-down processes in schizophrenia: A DCM study of ERPs. NeuroImage, 52(3), pp. 824–832. doi:10.1016/j.neuroimage.2009.12.086.
  42. Dima, D., Roiser, J.P., Dietrich, D.E., Bonnemann, C., Lanfermann, H., Emrich, H.M. … Dillo, W. (2009). Understanding why patients with schizophrenia do not perceive the hollow-mask illusion using dynamic causal modelling. NeuroImage, 46(4), pp. 1180–1186. doi:10.1016/j.neuroimage.2009.03.033.

Education

BSc Year 1

PS1009 Psychology at City

BSc Year 2

PS2004 Biological Psychology