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Optometry Professor awarded Wellcome Trust Health Innovation Challenge Fund

Wellcome Trust grant will be used to investigate a major cause of blindness known as uveitis

by George Wigmore (Senior Communications Officer)

Professor David Crabb from the Division of Optometry and Visual Science at City University London has been awarded a significant grant from the Wellcome Trust to investigate a major cause of blindness known as uveitis. The project is in partnership with the University of Birmingham and UCL and is due to start in June.

Awarded under the Health Innovation Challenge Fund, the project has been awarded £533,000 with around £100,000 coming to City for the computational and imaging aspects of the study. The full project title is Measuring Uveitis Activity Using Spectral Domain Optical Coherence Tomography.

Uveitis is a major cause of blindness in the working-age population and is a condition that results in inflammation inside the eye, but current treatment is unreliable and Professor Crabb and colleagues are aiming to improve the measurement of the disease in this new project.

Speaking about the study and Wellcome Trust award, David Crabb, Professor of Statistics and Vision Research at City University London said:

“We’re delighted to be awarded a grant from the Wellcome Trust to investigate an eye condition which is not particularly well known in the general population but which can cause debilitating blindness. Current measures of disease activity are subjective clinical estimates which are unreliable and this leads to under- and over-treatment of disease. As a result, in this project we will use an imaging technique to detect changes in the vitreous gel inside the eye to better measure the effect of disease and treatment.”

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