Centre for Applied Vision Research
  1. Visual Neuroscience and Psychophysics
  2. Ocular Optics and Instrumentation
  3. Ophthalmic Assessments and Patient Outcomes following Ophthalmic Interventions
  4. Visual Development and Plasticity
  5. Ophthalmic Public Health
  6. Measurement Techniques in Vision
Vision

Visual Development and Plasticity

The Visual Development & Plasticity Group investigates impairments in visual perception, cognitive functions and/or visuomotor control in patients (children and adults) with relatively common neuro-developmental disorders, such as amblyopia, autism spectrum disorder (ASD), and retinopathy of prematurity (ROP). Approaches include visual psychophysics, electrophysiology (EOG, ERG, VEP) and hand- and eye-movement recordings. Major research focuses involve detailed evaluations of the relative efficacies of conventional (i.e., refractive adaptation and patching) versus novel (perceptual learning) therapies in mediating the neuro-plasticity necessary to reverse the visual and visuomotor deficits associated with amblyopia, and applications aimed at enhancing understanding of the cellular pathologies of ASD and ROP and improving their electrodiagnosis.

Staff

Grants

2011-2015, Amblyopia:neural mechanisms of treatment Awarded to CE Stewart NIHR £99,000

2011-2015, Amblyopia:neural mechanisms of treatment extra . Awarded to CE Stewart NIHR £40,000

2011-2013, Curriculum Review for Evidence-based Practice in Australasian Optometry. Awarded to C Suttle, I Jalbert, P Hendicott, R Jacobs, B Junghans, K Pesudovs, M Pianta, F Stapleton, R Thompson, L Togher, H Weisinger. Australian Learning and Teaching Council (now the Office for Learning and Teaching) AUD 217,000

2010-2011, Effects of abnormal binocular vision on eye-hand voordination in children Awarded to S Grant & J Sloper (MEH) The Special Trustees of Moorfields Eye Hospital £25,006

2010, Major Research Equipment and Infrastructure Initiative Awarded to C Suttle, S Khuu, M Boon, L Asper University of New South Wales AUD 53,000

2009-2012, Visual Function in autism. Awarded to P. Constable College of Optometrists £30,000

2009-2014, Personalising patching for amblyopia treatment. Awarded to CE Stewart and MJ Moseley NIHR £215,249

2009-2010, A digital measuring spoon to optimise occlusion therapy Awarded to CE Stewart. Emerald Fund £40,000.

Publications

2013

Bokhary, K. A., Suttle, C., Alotaibi, A. G., Stapleton, F., & Boon, M. Y. (2013). Development and validation of the 21-item Children's Vision for Living Scale (CVLS) by Rasch analysis. Clinical and Experimental Optometry. Epub ahead of print

Errington, J. A., Menant, J. C., Suttle, C. M., Bruce, J., & Asper, L. J. (2013). The effects of vertical yoked prisms on gait. Investigative Ophthalmology and Visual Science, 54(6), 3949-3956

Stewart CE, Wallace MP, Stephens DA, Fielder AR, Moseley MJ, on behalf of the MOTAS cooperative. The effect of amblyopia treatment on stereoacuity. JAAPOS 2013;17:166-73

Suttle, C., Jalbert, I., & Alnahedh, T. (2013). Re: The evidence in evidence-based practice. Why the confusion?. Clinical and Experimental Optometry, 96(1), 130

Yeotikar, N. S., Khuu, S. K., Asper, L. J., & Suttle, C. M. (2013). Context and Crowding in Perceptual Learning on a Peripheral Contrast Discrimination Task: Context-Specificity in Contrast Learning. PLoS ONE, 8(5)

2012

Constable, PA., Gaigg, SB., Bowler, DM., Thompson, DA.(2012) Motion and pattern cortical potentials in adults with high-functioning autism spectrum disorders, Documenta Ophthalmologica 125(3); 219-227

Lai, X. J., Alexander, J., He, M. G., Yang, Z. K., & Suttle, C. (2012). A novel apparatus for interocular interaction evaluation in children with and without anisometropic amblyopia. Clinical and Experimental Optometry, 95(4), 410-420

Lai, X. J., Alexander, J., Ho, A., Yang, Z., He, M., & Suttle, C. (2012). Design and validation of a method for evaluation of interocular interaction. Optometry and Vision Science, 89(2), 183-196

Melmoth DR, Grant S (2012) 'Getting a grip; different actions and visual guidance of the thumb and finger in precision grasping' Experimental Brain Research 222: 265-276

Suttle, C. M., Jalbert, I., & Alnahedh, T. (2012). Examining the evidence base used by optometrists in Australia and New Zealand. Clinical and Experimental Optometry, 95(1), 28-36

2011

Boon, M. Y., Chan, K. Y., Chiang, J., Milston, R., & Suttle, C. (2011). EEG alpha rhythms and transient chromatic and achromatic pattern visual evoked potentials in children and adults. Documenta Ophthalmologica, 122(2), 99-113

Constable, PA. (2011), Nifedipine alters the light-rise of the electro-oculogram in man. Graefe's Archive for Clinical and Experimental Ophthalmology, 2011. 249(5): 677-684

Lai, X. J., Alexander, J., He, M., Yang, Z., & Suttle, C. (2011). Visual functions and interocular interactions in anisometropic children with and without amblyopia. Investigative Ophthalmology and Visual Science, 52(9), 6849-6859

Masgoret, X., Asper, L., Alexander, J., & Suttle, C. (2011). The development of crowding and interocular interactions in a resolution acuity task. Investigative Ophthalmology and Visual Science, 52(13), 9452-9456

Stewart CE, Fielder AR, Moseley MJ. (2011). Amblyopia therapy: an update Strabismus, 19;91-98

Suttle CM, Melmoth DR, Finlay AL, Sloper JJ, Grant S (2011) 'Eye-hand coordination skills in children with and without amblyopia'. Investigative Ophthalmology & Visual Science 52:1851-1864

Yeotikar, N. S., Khuu, S. K., Asper, L. J., & Suttle, C. M. (2011). Configuration specificity of crowding in peripheral vision. Vision Research, 51(11), 1239-1248

2010

Constable PA, Solomon JA, Gaig, S, Bowler DM (2010) Crowding and Visual Search in adults with high functioning autism spectrum disorder. Clin. Optom 2:93-103

Cui, Y., Stapleton, F., Suttle, C., & Bundy, A. (2010). Health- and vision-related quality of life in intellectually disabled children. Optometry and Vision Science, 87(1), 37-44

Grant S (2010) 'Cranial nerves supplying the extraocular muscles' Optometry Today 50:34-41 (NR)

Hilgetag CC, Grant S (2010) 'Cytoarchitectural differences are key determinants of laminar projection origins in the visual cortex'. NeuroImage 51:1006-1017

Masgoret, X., Asper, L., Alexander, J., & Suttle, C. (2010). Enhancement of resolution acuity in a half-binocular viewing condition. Investigative Ophthalmology and Visual Science, 51(11), 6066-6069

Suttle, C. M. (2010). Active treatments for amblyopia: A review of the methods and evidence base. Clinical and Experimental Optometry, 93(5), 287-299

2009

Boon, M. Y., Suttle, C. M., Henry, B. I., & Dain, S. J. (2009). Dynamics of chromatic visual system processing differ in complexity between children and adults. Journal of Vision, 9(6). Art no. 22

Moseley MJ, Fielder AR, Stewart CE (2009). The optical treatment of amblyopia. Optometry and Vision Science 86: 629-633

Stewart CE, Wilson CM, Fielder AR. (2009). A 3(1/2) year old girl presenting with strabismus. British Medical Journal 338:b68

Suttle, C. (2009). Visual acuity assessment in infants and young children. Clinical and Experimental Optometry, 84(6), 337-345

Suttle, C., Alexander, J., Liu, M., Ng, S., Poon, J., & Tran, T. (2009). Sensory ocular dominance based on resolution acuity, contrast sensitivity and alignment sensitivity. Clinical and Experimental Optometry, 92(1), 2-8

Whatham, A., Suttle, C., Blumenthal, C., Allen, J., & Gaskin, K. (2009). ERGs in children with pancreatic enzyme insufficient and pancreatic enzyme sufficient cystic fibrosis. Documenta Ophthalmologica, 119(1), 43-50

2008

Boon, M. Y., Henry, B. I., Suttle, C. M., & Dain, S. J. (2008). The correlation dimension: A useful objective measure of the transient visual evoked potential?. Journal of Vision, 8(1), 1-21

Cui, Y., Stapleton, F., & Suttle, C. (2008). Developing an instrument to assess vision-related and subjective quality of life in children with intellectual disability: Data collection and preliminary analysis in a Chinese population. Ophthalmic and Physiological Optics, 28(3), 238-246

Stewart CE, Gilchrist J, McGraw PV, Winn BW. (2008). Diagnostic accuracy of school vision screening. British and Irish Orthoptic Journal 5: 47-53

Vedamurthy, I., Suttle, C. M., Alexander, J., & Asper, L. J. (2008). A psychophysical study of human binocular interactions in normal and amblyopic visual systems. Vision Research, 48(14), 1522-1531