Clinical and Physiological Optics (CPO)

This is the largest research group and is involved in a number of ongoing socially-significant applied and clinical research projects that are supported mostly by EPSRC, MRC, CAA, DTI, Wellcome Trust, ophthalmic and pharmaceutical industry and a number of charities. The group is led by John Barbur (JLB) and includes Chris Hull (CCH), David Edgar (DE), Luis Diaz-Santana (LS), Jennie Birch (JB), Alister Harlow (AH), David Thomson(DT), Geoffrey Arden (GBA), Roger Buckley (RB) and Catharine Chisholm (CC). The CPO group relies heavily on non-invasive techniques based largely on visual psychophysics and objective assessment through measurement of visually evoked involuntary signals. The members of this group have similar interests and work closely with the VPP group, but the emphasis is more on the use and exploitation of basic research findings for industrial and clinical research.

Further information:

• Research achievements
• Future research directions
• Interdisciplinary / collaborative research studies

• Limits of functional, diffraction-limited vision effects of scattered light and aberrations
• The light scattering characteristics of the eye
• Corneal Topography
• Clinical Optics/Instrumentation
• Posterior Capsular Opacification
• Polypseudophakia
• Osteo-Odonto Keratoprosthesis Optics

• Learning from the pupil - studies of basic mechanisms and clinical applications
• Insights into different uses of chromatic signals in human vision
• Minimum colour vision requirements for pilots - a study of functional aspects of chromatic signals in human vision
• A study of mesopic visual performance - the development of adequate scales of luminous efficiency in the mesopic range
• Blindsight and residual vision studies in patients with damaged central visual pathways

• A Clinical Trial of a New Technique to Prevent Diabetic Retinopathy
• The Effect of Alcohol on the EOG of Normal and Abnormal Human Retinas
• Comparison of Effects of Light and Alcohol on the EOGs of different species
• Colour Mechanisms in the ERG and Changes to Colour Contrast Sensitivity in Disease

• Loss of chromatic and achromatic sensitivity in glaucoma
• "EyeNET" Funded Research Projects
• Audit of Clinical Colour Vision Test Efficiency and Occupational Colour Vision Standards
• Development of new colour vision tests for the assessment of acquired colour deficiency
• Defective Colour Vision in Medical Practice

John Barbur | Chris Hull | David Edgar | David Thomson | Geoffrey Arden | Roger Buckley Applied Vision Research Centre